CAS: 19533-92-7; 9,10-Dihydroxy-5A,5B,8,8,11A-Pentamethyl-1-(Prop-1-En-2-yl)Icosahydro-3Ah-Cyclopenta[a]Chrysene-3A-Carboxylic Acid
该化合物是一种自然产生的有机化合物,被归类为苯酸,主要来自某些植物材料的水解,特别是与橡树有关的植物材料,其特点是芳香结构,包括附于苯环的氢氧基(OH),有助于其化学反应和潜在的生物活动;甲硫酸的抗氧化特性,在保护细胞免受氧化性压力方面可能起到作用;此外,已研究过它潜在的抗微生物和抗炎影响,使其在各个领域,包括药理学和食品科学中引起兴趣;有机溶剂中的硫酸的溶性及其在特定条件下的稳定性,对于其研究和工业的应用十分重要;总的来说,甲硫酸是一种重要的化合物,对自然产品化学具有潜在的健康惠益和应用.
- 英文名称9,10-Dihydroxy-5A,5B,8,8,11A-Pentamethyl-1-(Prop-1-En-2-yl)Icosahydro-3Ah-Cyclopenta[a]Chrysene-3A-Carboxylic Acid
- 中文名称麦珠子酸
- IUPAC名称9,10-dihydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic acid
- 其它别名2Alpha-Hydroxybetulinic Acid; Lup-20(29)-En-28-Oic Acid, 2,3-Dihydroxy- (8Ci); (2,3)-2,3-Dihydroxylup-20(29)-En-28-Oic Acid; 3Ah-Cyclopenta[a]Chrysene, Lup-20(29)-En-28-Oic Acid Deriv.; 2-Hydroxybetulinic Acid; Alphitolic Acid
- CAS编号19533-92-7
- MFCD编号:MFCD17214912
- 分子式:C30H48O4分子量:472.71
- 产品CID: 991886
- 产品分类天然产物 → 萜类
物理性质
MSDS等安全信息
上下游产品
2α,3β-diacetoxylup-20(29)-en-28-oic acid 2)-β-D-glucopyranosyl)oxy]lup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester2α-hydroxy-3β-[(O-β-D-xylopyranosyl-(1-2)-β-D-glucopyranosyl)oxy]lup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester 4)-O-β-D-xylopyranosyl-(1->2)-β-D-glucopyranosyl)oxy]-2α-hydroxylup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester3β-[(O-α-L-arabinopyranosyl-(1-4)-O-β-D-xylopyranosyl-(1-2)-β-D-glucopyranosyl)oxy]-2α-hydroxylup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester 4)-O-β-D-xylopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->4)]-β-D-glucopyranosyl)oxy]-2α-hydroxylup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester3β-[(O-α-L-arabinopyranosyl-(1-4)-O-β-D-xylopyranosyl-(1-2)-O-[β-D-xylopyranosyl-(1-4)]-β-D-glucopyranosyl)oxy]-2α-hydroxylup-20(29)-en-28-oic acid α-L-rhamnopyranosyl ester合成工艺路线路线简述
📜2α,3β-Diacetoxylup-20(29)-En-28-Oic Acid置于水,Sodium Hydroxide,盐酸体系中,用 甲醇,水 用作溶剂,化学反应 2.0H,以97%的收率获得麦珠子酸
参考文献:有效获得异构体2,3-二羟基lupanes:首次合成磷酸
标题:有效获得异构体2,3-二羟基lupanes:首次合成磷酸
摘要:环烷酸(3)是天然存在的戊烷型五环三萜,具有多种药理特性.3的有效合成已从10步中完成,从容易获得的二酮11开始,总产率为19%.还开发了关键中间体17的替代方法,基于该方法,可以从10开始以10步获得3,总产率为26%(从11开始).此外,七其他异构-2,3-二羟基lupanes 4-10已被合成.合成的三萜3-10 评估了它们对兔肌肉gpa(rmgpa)的抑制活性,其中一些对rmgpa表现出中等的抑制活性.
Doi:10.1016/j.Tet.2009.07.047
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Expedient Synthesis Of Alphitolic Acid And Its Naturally Occurring 2-O-Ester Derivatives作者:Somin Park,Jihee Cho,Hongjun Jeon,Sang Hyun Sung,Seunghee Lee,Sanghee Kim |发布日期:2019.4.26
摘要:Expedient Synthesis Of Alphitolic Acid (1) As Well As Its Natural C-3-Epimer And 2- O-Ester Derivatives Was Accomplished In A Few Steps From The Readily Commercially Available Betulin (9). A Rubottom Oxidation Delivered An α-Hydroxy Group In A Stereo- And Chemoselective Manner. The Diastereoselective Reduction Of The α-Hydroxy Ketone Was Key To Accessing The 1,2-Diol Moiety Of This Class Of Natural Products
合成参考文献
参考文献:10.1016/s0031-9422(01)00180-7
摘要:Gu JQ, Park EJ, Luyengi L, Hawthorne ME, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity. Phytochemistry. 2001 Sep;58(1):121–7. doi: 10.1016/s0031-9422(01)00180-7.
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