CAS: 16277-06-8; 2-Methylpyrrolidine-2-Carboxylic Acid

相似化合物

1423025-85-7 123053-48-5 63399-77-9

上下游产品

DL-(α-methyl)proline amide 5-chloro-2-pentanone 1-benzyl-2-methylpyrrolidine-2-carbonitrile 1-benzyl-2-methylpyrrolidine-2-carboxamide(2-methylpyrrolidin-2-yl)methanol

📜(1S)-N-(1'-Phenylethyl)-α-Methylprolinamide置于硫酸,Palladium 10% On Activated Carbon,水,氢气,溶剂黄146体系中,用 甲醇,乙酸乙酯 用作溶剂,化学反应 9.5H,反应生成(2S)-2-甲基-2-吡咯烷鎓羧酸酯
参考文献:Ep2716629
标题:Ep2716629

专利信息

专利号:WO-2025215225-A1
优先权日:2024-04-12
标题:Method for the synthesis of 5-methoxy-2-(2h-1,2,3-triazol-2-yl)benzoic acid, a sodium salt of said acid as a synthetic intermediate, and use of the acid or the salt thereof in the preparation of daridorexant and certain intermediates in the synthesis thereof
发明人：AKHATOU ABDESLAM; BALLETTE ROBERTO
权利人:MOEHS IBERICA S L
摘要:The invention relates to a method for the synthesis of 5-methoxy-2-(2H-1,2,3-triazol-2-yl)benzoic acid, to the sodium salt of said acid as a synthetic intermediate, and to the use of the acid or the salt thereof in the preparation of daridorexant and certain intermediates in the synthesis thereof.

专利号:US-10087221-B2
优先权日:2013-03-21
标题 :Synthesis of hydantoin containing peptide products
发明人：HENKEL BERND
权利人:SANOFI AVENTIS DEUTSCHLAND
摘要:The present invention relates to a method of synthesizing a peptide product comprising at least one hydantoin group. The peptide product may be used as a reference material for the quality control of pharmaceutical peptides, particularly for the quality control of exendin peptides. Further, the invention relates to hydantoin building blocks, a method for manufacturing such building blocks and their use for the synthesis of peptide products.

专利号:US-2012095211-A1
优先权日:2010-09-22
标 题 :Substituted proline inhibitors of hepatitis c virus replication
发明人：BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D
权利人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D; INTERMUNE INC
摘要:The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IIIb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. The embodiments also provide methods for the synthesis of subject compounds and intermediates in the synthetic methods.

专利号:CN-114933557-A
优先权日:2022-03-02
标 题:A novel method for the synthesis of (S)-2-methylproline in high-throughput microchannels

专利号:US-9732137-B2
优先权日:2007-12-28
标 题 :Semi-recombinant preparation of GLP-1 analogues
发明人：LAU JESPER FAERGEMAN; ANDERSEN ASSER SLOTH; BLOCH PAW; LAU JESPER; GARIBAY PATRICK WILLIAM; KRUSE THOMAS; NØRBY INGA SIG NIELSEN; JESSEN CLAUS ULRICH; CHRISTENSEN CASPAR; NORRILD JENS CHRISTIAN
权利人:LAU JESPER FAERGEMAN; ANDERSEN ASSER SLOTH; BLOCH PAW; LAU JESPER; GARIBAY PATRICK WILLIAM; KRUSE THOMAS; NØRBY INGA SIG NIELSEN; JESSEN CLAUS ULRICH; CHRISTENSEN CASPAR; NORRILD JENS CHRISTIAN; NOVO NORDISK AS
摘要:A semi-recombinant method for the production of GLP-1 analogues and derivatives with non-proteogenic amino acids in the N-terminal part combining the use of recombinant expression techniques and chemical peptide synthesis.

专利号:EP-2976331-A1
优先权日:2013-03-21
标题:Synthesis of hydantoin containing peptide products