CAS: 1112-48-7; Bromotriethylsilane

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CAS号2117-17-1 [amino(diethyl)... | CAS号617-86-7 三乙基硅烷 | CAS号994-30-9 三乙基氯硅烷 | CAS号1633-09-6 (价格有效051118) | CAS号994-49-0 六乙基二硅氧烷 | CAS号506-96-7 乙酰溴 | CAS号1112-49-8 triethyliodosilane | CAS号1777-03-3 (三乙基硅烷基)乙炔 | CAS号17947-98-7 BIS(TRIETHYLSIL... | CAS号18279-65-7 trichloro(2-tri... | CAS号74-96-4 溴乙烷 | CAS号7550-35-8 溴化锂 | CAS号994-49-0 六乙基二硅氧烷 | CAS号994-30-9 三乙基氯硅烷 | CAS号597-52-4 三乙基硅烷醇 | CAS号617-86-7 三乙基硅烷 | CAS号358-43-0 三乙基氟硅烷

📜四乙基硅烷置于氘代苯,1,2-二溴乙烷体系中,用> 95 %的收率获得三乙基溴硅烷
参考文献:芳烃离子催化全烷基化硅烷的卤代脱烷基化
标题:芳烃离子催化全烷基化硅烷的卤代脱烷基化
摘要:"有机硅"在自然界中并不存在,但现代化学很难想象没有硅与碳结合的情况.虽然含硅商品化学品(例如通过"直接工艺" 1,2,3,4产生的那些)看起来很简单,但选择性制备芳基取代和烷基取代(官能化)硅化合物(称为硅烷)并非易事.氯硅烷如 Me 4− N Sicl N ( N = 1-3) 以及 Sicl 4 ( N = 4) 是合成含硅分子的常见起点.然而这些方法常常遇到具有挑战性的分离问题5 .相反,具有四个烷基的硅烷被认为是合成的死角.在这里,我们介绍了芳烃离子催化的卤代脱烷基化反应,可有效地将 Me 4 Si 和相关的季硅烷转化为各种官能化衍生物.该反应使用烷基卤和芳烃(共)溶剂:烷基卤是卤化物源,最终与芳烃进行弗里德尔-克来福特烷基化以再生催化剂6,而芳烃离子则充当强布朗斯台德酸原脱烷基化步骤7 .例如,在硅药物前体的合成中,证明了自上而下的卤代烷基化方法相对于报道的自下而上程序的优势.此外,连接到烷基链上的相当惰性的me
Doi:10.1038/s41586-023-06646-9

专利信息

专利号:WO-2022256490-A9
优先权日:2021-06-03
标题:Improved synthesis of phosphoramidates for the treatment of hepatitis b virus
发明人：LOCKWOOD MARK
权利人:ANTIOS THERAPEUTICS INC
摘要:The synthesis of phosphoramidate prodrugs useful in the treatment of viral infections is disclosed. Specifically, an improved synthesis of phosphoramidate nucleotides useful in the treatment of Hepatitis B virus is disclosed.

专利号:US-10669160-B2
优先权日:2018-04-30
标题:Heterogeneous wet synthesis process for preparation of high purity tungsten pentahalide
发明人：LIU YUMIN; LI FENG; WAN ZHIWEN; FAFARD CLAUDIA; WIESE STEFAN; HUSSON GUILLAUME; NIKIFOROV GRIGORY; SUI BIN; GIRARD JEAN-MARC
权利人:AIR LIQUIDE; AIR LIQUIDE AMERICAN
摘要:Synthesis of tungsten pentahalide compositions having low impurity profiles are disclosed. The specific impurity profile permits deposition of high purity tungsten-containing films using vapor deposition processes or other semiconductor manufacturing processes without introduction of performance-impacting contaminants.

专利号:WO-0212185-A1
优先权日:2000-08-10
标 题:Process for preparing 2,3-diaminopropanols and synthesis of other compounds using 2,3-diaminopropanols
发明人：LEE WON KOO; SHIN SEONG-HO; HA HYUN-JOON
权利人:CHEMBIONEX CO LTD; HANSOL CHEMIENCE CO LTD; LEE WON KOO; SHIN SEONG HO; HA HYUN JOON
摘要:The invention relates to a process for producing 2,3-diaminopropanol of formula (II) from aziridine of formula (I) wherein, R1 is selected from a group consisting of hydrogen, alkyl, cycloalkyl, acyl, aryl, hydrocarbon residues, aralkyl, and those groups substituted with suitable substituent(s); R2 is selected from a group consisting of hydrogen, alkyl, cycloalkyl, C¿2?-C5-alkenyl, aralkyl which may be optionally substituted with suitable substituent(s), aryl which may be optionally substituted with suitable substituent(s), and heteroaryl which may be optionally substituted with suitable substituent(s); each of R?3 and R4¿ is independently selected from a group consisting of hydrogen, C¿1?-C12 alkyl, C1-C12 alkylcarbonyl, C1-C12 alkyloxycarbonyl, aryl, mono- or di(C1-C12)alkylamino, mono- or di(C1-C12)amino carbonyl, wherein C1-C12 may be optionally substituted, or R?3 and R4¿, together with nitrogen atom which they are attached to, may form pyrrolidinyl, piperidinyl, morpholinyl, azido or mono- or di(C¿1?-C12)alkylamino C1-C4 alkylidene.

专利号:US-4251442-A
优先权日:1978-12-07
标题:Method for synthesis of penicillin
发明人：MORITA YOSHIHARU; ITAGAKI TAKAHARU; ITO TSUYOSHI; WADA SHIGENORI
权利人:MITSUBISHI CHEM IND
摘要:This invention relates to a method for synthesizing a penicillin by reacting a silylate of 6-aminopenicillanic acid and a carboxylic acid halide in the presence of an insoluble weakly basic resin having a three-dimensional structure.

专利号:US-4914233-A
优先权日:1988-03-01
标题:Synthesis of beta-thymidine
发明人：FRESKOS JOHN N; SENARATNE K PUSHPANANDA A
权利人:ETHYL CORP
摘要:A process is provided in which a mixture of alpha- and beta-anomers is converted selectively to the desired beta-thymidine. The process involves the following steps: (a) converting a mixture of alpha- and beta-anomers of tetra-O-acylribofuranose to tri-O-acyl-β-ribothymidine; (b) converting tri-O-acyl-β-ribothymidine to β-ribothymidine; (c) converting β-ribothymidine to 2,2'-anhydro-β-thymidine; (d) converting 2,2'-anhydro-β-thymidine to 2'-halo-2'-deoxy-5-methyluridine; and (e) converting 2'-halo-2'-deoxy-5-methyluridine to beta-thymidine. The mixture of alpha- and beta-anomers of tetra-O-acylribofuranose may be produced by any suitable procedure such as by converting lower alkyl ribofuranoside to the tetra-O-acylribofuranose mixture. The lower alkyl ribofuranosides may in turn be produced by various methods. However, a desirable way of effecting this conversion involves use of D-ribose as the starting material which is converted to the lower alkyl ribofuranoside.

专利号:US-5399649-A
优先权日:1993-05-28
标 题 :Method for the preparation of diorganopolysiloxanes
发明人：OKAWA TADASHI
权利人:DOW CORNING TORAY SILICONE
摘要:A method for the high-purity synthesis of a diorganopolysiloxane having a functional group at only one molecular chain terminal, that is characterized by the preliminary silylation with a silylating agent of the silanol group-containing impurity present in the cyclic trisiloxane, and that is characterized by preliminarily converting the silanol group-containing impurity in the cyclic trisiloxane into a lithiated material by lithiation with an organolithium compound and then silylating this lithiated material using a silylating agent that contains silicon-bonded halogen.