CAS: 1005-56-7; O-Phenyl Carbonochloridothioate

相似化合物

940-58-9 937-64-4 2812-83-1

上下游产品

thiophosgene phenol tetrachloromethane chloroformmethylene chloride O-phenyl N,N-dimethylthi°Carbamate N-phenyl-O-phenylthi°Carbamate O-phenyl N-methyl-N-phenylthi°Carbamate

苯酚 反应生成硫代氯甲酸苯酯
参考文献:Bay,Elliott
标题:Bay,Elliott

专利信息

专利号:US-8835477-B2
优先权日:2009-10-06
标题 :Method for the synthesis of 2-thiohistidine and the like
发明人：ERDELMEIER IRÈNE; DAUNAY SYLVAIN
权利人:ERDELMEIER IRÈNE; DAUNAY SYLVAIN; TETRAHEDRON
摘要:Methods for the synthesis of 2-thiohistidine or a derivative thereof of the formula (I), or of a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, from a compound of the formula (II) or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, by cleavage reaction in the presence of a thiol at a temperature higher than or equal to 60° C. The invention also relates to compounds of the formula (II) and a method for the synthesis thereof.

专利号:US-11858953-B2
优先权日:2018-04-04
标 题:Compositions and methods for synthesis of phosphorylated molecules
发明人：CHAPUT JOHN; LIAO JEN-YU; BALA SAIKAT
权利人:UNIV CALIFORNIA
摘要:The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.

专利号:US-5506349-A
优先权日:1992-05-13
标 题 :Chemical synthesis of 2', 3'-dideoxycytidine
发明人：MATULIC-ADAMIC JASENKA
权利人:RIBOZYME PHARM INC
摘要:Method for synthesis of 2',3'-dideoxycytidine by providing 5'-silylated-2',3'-dideoxyuridine as an intermediate.

专利号:US-7767826-B2
优先权日:2007-10-05
标题 :Process for the synthesis of L-(+)-ergothioneine
发明人：TRAMPOTA MIROSLAV
权利人:PHARMATECH INTERNATIONAL INC
摘要:This invention relates to a novel process for the preparation of optically pure L-(+)-ergothioneine. The process for the chemical synthesis of L-ergothioneine comprises steps which consist of reacting L-histidine alkyl ester with an acid halide, chloroformate or pyrocarbonate in the presence of a base, hydrolysis of the alkyl-(S,Z)-2,4,5-triamidopent-4-enoate to obtain a (S)-alkyl 2,5-diamido-4-oxopentanoate, acid catalyzed hydrolysis of the (S)-alkyl 2,5-diamido-4-oxopentanoate followed by reaction with a metal thiocyanate to obtain the thiohistidine, protection of the sulfur of thiohistidine as the tert-butyl thioether, dialkylation of the primary amine to obtain a tertiary amine, quaternization of the tertiary amine, and removal of the protecting group to obtain the desired (S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trialkylammonio)propanoate (I). This process affords a better yield and is capable of practical application at large scale.

专利号:WO-9323413-A1
优先权日:1992-05-13
标 题:Synthesis of nucleotide monomers
发明人：BEIGELMAN LEONID; MATULIC-ACADEMIC JASENKA
权利人:RIBOZYME PHARM INC
摘要:Methods for synthesis of 2',3'-dideoxycytidine, 2',3'-dideoxyguanosine, 2',3'-dideoxyadenosine, 2',3'-dideoxyinosine and 2',3'-dideoxyguanosine, and 3'-O-benzoyl-2'-deoxyribonucleoside.

专利号:US-5925762-A
优先权日:1996-09-17
标 题:Practical synthesis of urea derivatives
发明人：THAVONEKHAM BOUNKHAM
权利人:BOEHRINGER INGELHEIM CA LTD
摘要:A very mild and efficient approach for the synthesis of ureas is described. Phenyl carbamates were used as intermediates for the preparation of N,N'- substituted ureas. The carbamates were treated with an approximate stoichiometric amount of amine in dimethyl sulfoxide at ambient temperature, generating the ureas in high yield. The reaction was simple, safe, fast, inexpensive, and amenable to large scale production of the product.