CAS: 84745-94-8; 17-Acetyl-3,8,14,17-Tetrahydroxy-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]Phenanthren-12-Yl 4-Hydroxybenzoate
该化合物是属于三叶类的化学化合物,这些化合物是自然产生的化合物,经常在各种植物中发现.这种物质的特点是复杂的分子结构,典型的特点是多环和有助于其生物活动的功能组.青阳正宁由于其潜在的治疗特性,包括抗炎,抗氧化剂和抗癌效应,对药理研究产生了兴趣.其行动机制可能包括调和各种信号路径和与细胞目标的相互作用.此外,该化合物的溶性,稳定性和生物利用率是影响其在生物系统中功效的重要因素.与许多自然产品一样,提取和净化过程会影响青阳石亨宁的产量和质量,因此研究人员必须优化这些方法,以便进一步研究.总的来说,青阳琴宁是天然产品化学和药理学中一个很有希望的研究领域.
- 英文名称17-Acetyl-3,8,14,17-Tetrahydroxy-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]Phenanthren-12-Yl 4-Hydroxybenzoate
- 中文名称青阳参苷元
- IUPAC名称17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-12-yl 4-hydroxybenzoate
- CAS编号84745-94-8
- MFCD编号:MFCD09752816
- 分子式:C28H36O8分子量:500.59
- 产品CID: 1837234
- 产品分类天然产物 → 甾体化合物
物理性质
MSDS等安全信息
上下游产品
4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1->4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate(3β,12β,14β,17α)-3-{[2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1-4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate 4)-2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1->4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate(3β,12β,14β,17α)-3-{[2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1-4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate 4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1->4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate(3β,12β,14β,17α)-3-{[2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-β-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl-(1-4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-8,14,17-trihydroxy-20-oxopregn-5-en-12-yl 4-hydroxybenzoate 4)-β-D-oleandropyranosyl-(1->4)-β-D-cymaropyranosyl-(1->4)-β-D-digitoxopyranosideqingyangshengenin-3-O-β-D-cymaropyranosyl-(1-4)-β-D-oleandropyranosyl-(1-4)-β-D-cymaropyranosyl-(1-4)-β-D-digitoxopyranoside合成工艺路线路线简述
📜Qingyangshengenin 3-O-β-D-Glucopyranosyl-(1->4)-β-D-Glucopyranosyl-(1->4)-β-D-Cymaropyranosyl-(1->4)-β-D-Oleandropyranosyl-(1->4)-β-D-Digitoxopyranoside置于盐酸体系中,用 甲醇 作为反应溶剂,化学反应 0.25H,反应生成 青阳参苷元
参考文献:New Pregnane Glycosides From The Roots Of Cynanchum Otophyllum
标题:New Pregnane Glycosides From The Roots Of Cynanchum Otophyllum
摘要:Six New Pregnane Glycosides With An Acyl At C-12 And A Straight Sugar Chain At C-3,Namely Otophyllosides H-M (1-6),Were Isolated From The Roots Of Cynanchum Otophyllum (Asclepiadaceae) Collected From Eryuan County In Yunnan Province Of China. Their Structures Were Characterized To Be Qingyangshengenin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(L-> 4)-Beta-D-Digitoxopyranoside (1),Qingyangshengenin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-4)-0-D-Cymaropyranosyi-(1-4)-P-D-Digitoxopyranoside (2),Qingyangshengenin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Oleandropyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Digitoxopyranoside (3),Qingyangshengenin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Thevetopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl(1-> 4)-Beta-D-Digitoxopyranoside (4),Caudatin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Oleandropyranosyl-(1-> 4)-Beta-D-Cymaropyranoside (5),Caudatin 3-0-Beta-D-Glucopyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Oleandropyranosyl-(1-> 4)-Beta-D-Cymaropyranosyl-(1-> 4)-Beta-D-Cymaropyranoside (6),Respectively,On The Basis Of Detailed Spectroscopic Analysis And Chemical Method. (C) 2007 Elsevier Inc. All Rights Reserved.
DOI:10.1016/j.Steroids.2007.06.001
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.bmc.2017.04.045
摘要:Huang LJ, Chen SR, Yuan CM, Gu W, Guo BJ, Wang YT, Wang Y, Hao XJ. C21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents. Bioorg Med Chem. 2017 Jul 01;25(13):3512–24. doi: 10.1016/j.bmc.2017.04.045.
参考文献:10.1016/j.bmc.2021.116581
摘要:Li XS, Chen TJ, Xu ZP, Long J, He MY, Zhan HH, Zhuang HC, Wang QL, Liu L, Yang XM, Tang JS. Synthesis and biological evaluation of 3β-O-neoglycosides of caudatin and its analogues as potential anticancer agents. Bioorg Med Chem. 2022 Jan 15;54():116581. doi: 10.1016/j.bmc.2021.116581.
📝 需求与反馈
尽可能描述清楚需求与问题信息
