CAS: 78-99-9; 1,1-Dichloropropane

相似化合物

4279-22-5 598-77-6 3175-23-3

上下游产品

propane propionaldehyde propenyl chloride bromodichloromethane propane 1,1-difluoropropane 1-chloro-1-fluoro-propane 1,1,2-trichloropropane

📜丙烷 反应生成 1,1-二氯丙烷
参考文献:Hass Et Al.,Industrial And Engineering Chemistry,1936,Vol. 28,P. 1179
标题:Hass Et Al.,Industrial And Engineering Chemistry,1936,Vol. 28,P. 1179

专利信息

专利号:US-10981922-B2
优先权日:2012-04-26
标题 :Synthesis of lactams
发明人：TAVARES FRANCIS XAVIER
权利人:TAVARES FRANCIS XAVIER
摘要:Methods for the synthesis of lactams are presented whereby a carboxylic acid of the formula HOOC—OR—NH-LG, wherein OR is an organic moiety and LG is a leaving group, is reacted with an acid, such as an organic acid, in particular a strong acid, and a dehydrating agent, which may be one in the same such as a strong acid anhydride, such that the amount of acid added allows for the desired transformation to take place without the loss of the leaving group (LG) before the cyclization, and recovering the lactam.

专利号:US-2016257688-A1
优先权日:2013-10-24
标 题 :Process for Synthesis of Lactams
发明人：TAVARES FRANCIS XAVIER
权利人:TAVARES FRANCIS XAVIER
摘要:Methods for the synthesis of lactams are presented whereby a carboxylic acid of the formula HOOC—OR—NH-LG, wherein OR is an organic moiety and LG is a leaving group, is reacted with an acid, such as an organic acid, in particular a strong acid, and a dehydrating agent, which may be one in the same such as a strong acid anhydride, such that the amount of acid added allows for the desired transformation to take place without the loss of the leaving group (LG) before the cyclization, and recovering the lactam such as that of the formula (a), provided herein, wherein G represents the atom(s) needed to form a closed ring.

专利号:WO-9006311-A1
优先权日:1988-11-29
标 题 :Synthesis of (-)-swainsonine and intermediate compounds employed in such synthesis
发明人：CHA JIN KUN; BENNETT RICHARD BERNARD III
权利人:UNIV VANDERBILT
摘要:A method of synthesizing swainsonine and its analogues employing a unique intermediate imine and a unique intermediate enamide.

专利号:US-6906046-B2
优先权日:2000-12-22
标题 :Pharmaceutical uses and synthesis of benzobicyclooctanes
发明人：JACKSON RANDY W; DARWISH IHAB; BAUGHMAN TED A; HOWBERT J JEFFRY
权利人:CELLTECH R & D INC
摘要:Benzobicyclooctane compounds, their use in inhibiting cellular events involving TNF-α and IL-8, and in the treatment of inflammation events in general; a combinatorial library of diverse bicyclooctanes and process for their synthesis as a library and as individual compounds.

专利号:US-2003157061-A1
优先权日:2001-12-05
标 题 :Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor
发明人：BENNETT DENNIS A
权利人:PHARMACIA CORP
摘要:A method for the prevention, treatment, or inhibition of pain, inflammation, or inflammation-related disorder and for the prevention, treatment, or inhibition of a cardiovascular disease or disorder in a subject that is in need of such prevention, treatment or inhibition, involves the administration to the subject of a cyclooxygenase-2 selective inhibitor or prodrug thereof and a TNFα antagonist. A method can also involve the treatment, prevention, or inhibition of cancer in a subject in need of such treatment, prevention, or inhibition, by administering to the subject a cyclooxygenase-2 selective inhibitor or prodrug thereof and a TNFα antagonist which is selected from the group consisting of a compound that affects the synthesis of TNFα, a compound that inhibits the binding of TNFα with a receptor specific for TNFα, and a compound that interferes with intracellular signaling triggered by TNFα binding with a receptor. Compositions, pharmaceutical compositions and kits that can be used with the methods are also described.

专利号:US-2003232996-A1
优先权日:2001-04-20
标题:Regioselective synthesis of 3,4-di{(carboclyl or heterocyclyl)thiophenes
发明人：BROWN DAVID L; LUDWIG CINDY L
摘要:A novel process for preparing 3,4-di(carbocyclyl or heterocyclyl)thiophenes comprising reacting a compound of Formula IV with a ring cyclizing reagent to form the compound of Formula V to yield a compound of Formula V wherein R 1 , R 2 and R 3 are as defined in the specification.