CAS: 6264-98-8; 3-(O-Tolylamino)Phenol

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CAS号95-46-5 2-溴甲苯 | CAS号591-27-5 间氨基苯酚 | CAS号95-49-8 邻氯甲苯 | CAS号101-02-0 亚磷酸三苯酯 | CAS号95-53-4 邻甲苯胺 | CAS号108-46-3 间苯二酚 | CAS号10294-56-1 亚磷酸 | CAS号102-85-2 亚磷酸三丁酯 | CAS号762-04-9 亚磷酸二乙酯 | CAS号260-94-6 吖啶

📜2-溴甲苯,3-氨基苯酚置于chloro[2-(Dicyclohexylphosphino)-3,6-Dimethoxy-2',4',6'-Triisopropyl-1,1'-Biphenyl][2-(2-Aminoethyl)Phenyl]Palladium(Ll),Sodium T-Butanolate体系中,用 1,4-二氧六环 作为反应溶剂,化学反应 1.0H,以86%的收率获得产物邻甲基间羟基二苯胺
参考文献:Orthogonal Cu-And Pd-Based Catalyst Systems For The O-And N-Arylation Of Aminophenols
标题:Orthogonal Cu-And Pd-Based Catalyst Systems For The O-And N-Arylation Of Aminophenols
摘要:O-Or N-Arylated Aminophenol Products Constitute A Common Structural Motif In Various Potentially Useful Therapeutic Agents And/or Drug Candidates. We Have Developed A Complementary Set Of Cu-And Pd-Based Catalyst Systems For The Selective O-And N-Arylation Of Unprotected Aminophenols Using Aryl Halides. Selective O-Arylation Of 3-And 4-Aminophenols Is Achieved With Copper-Catalyzed Methods Employing Picolinic Acid Or Cydmeda,Trans-N,N'-Dimethyl-1,2-Cyclohexanediamine,Respectively,As The Ligand. The Selective Formation Of N-Arylated Products Of 3-And 4-Aminophenols Can Be Obtained With Brettphos Precatalyst,A Biarylmonophosphine-Based Palladium Catalyst. 2-Aminophenol Can Be Selectively N-Arylated With Cui,Although No System For The Selective O-Arylation Could Be Found. Coupling Partners With Diverse Electronic Properties And A Variety Of Functional Groups Can Be Selectively Transformed Under These Conditions.
DOI:10.1021/ja9081815

专利信息

专利号:US-4169832-A
优先权日:1975-09-05
标题 :Disazo and trisazo intermediates for polyazo dyes containing a stilbenyl or 2,2'-disulfostilbenyl radical
发明人：VOGEL CLAUDE; WICKI HEINZ
权利人:SANDOZ AG
摘要:Disclosed are compounds of the formula, ##STR1## wherein THE X's are the same and are hydrogen or --SO 3 M, n Y is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, hydroxy, halogen, --COOM or --SO 3 M, n K 1 and K 2 are the same or different and are both radicals of a coupling component, n Either A 1 is --SO 3 M and one of B 1 and C 1 is --SO 3 M, the other being hydrogen, n Or A 1 and C 1 are both hydrogen and B 1 is --SO 3 M, and n M is hydrogen or a non-chromophoric cation, their production and use in dyeing anionic dyeable substrates, for example, natural and regenerated cellulose, natural and synthetic polyamides, polyurethanes, polypropylene modified to contain basic groups, anodized aluminum, paper and, particularly, leather. The dyes are well-soluble in water, possess good resistance to acid, have relatively high substantivity especially to paper and leather and give good penetration dyeings with leather. n Compounds of the formula ##STR2## wherein Q is --NH 2 , --NO 2 , acylamino or K 3 --Nâ•?N--, n wherein K 3 is a coupling component radical free of diazotizable amino groups, n Q is --NH 2 , --NO 2 , acylamino or --Nâ•?N--K 4 , n wherein K 4 is a coupling component radical free of diazotizable amino groups, n with the proviso that when Q is K 3 --Nâ•?N--, Q' is amino, nitro or acylamino, and n A 1 , b 1 , c 1 , each X and Y are as defined above, are useful as intermediates in the synthesis of the polyazo cmpounds.