CAS: 57105-45-0; N-(3-Indolylacetyl)-L-Isoleucine
该化合物是植物荷尔蒙3-乙酸(IAA)和氨基酸L-solecine(IAA)的生物活性结合物,作为聚氨酸L-solecine的一种关键代谢物,它在调节植物生长和发育方面发挥着关键作用.该化合物因其稳定性和与助生受体的具体互动,在辅助信号和新陈代谢研究中特别重要.其特性完善的结构和高纯度对植物生理学,荷尔蒙迁移机制和应激反应途径的研究很有价值.同源体对酶退化的抗力增强了其在需要长期助产物活动的实验应用中的效用.
- 英文名称N-(3-Indolylacetyl)-L-Isoleucine
- 中文名称N-(3-吲哚乙酰基)-L-异亮氨酸
- IUPAC名称(2-(1H-indol-3-yl)acetyl)-L-isoleucine
- 其它别名N-(3-Indolylacetyl)-L-Isoleucine, ; Iaa-L-Ile; N-[1-Hydroxy-2-(1H-Indol-3-yl)Ethylidene]Isoleucine; (2S,3S)-2-[[2-(1H-Indol-3-yl)Acetyl]Amino]-3-Methylpentanoic Acid; L-Isoleucine, N-(1H-Indol-3-Ylacetyl)- (9
- CAS编号57105-45-0
- MFCD编号:MFCD00075401
- 分子式:C16H20N2O3分子量:288.35
- 产品CID: 1545592
- 产品分类有机原料→生命科学→氨基酸及其衍生物→异亮氨酸及其衍生物
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专利信息
专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
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主要参考文献
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.合成参考文献
参考文献:10.1038/s41592-019-0358-2]
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