专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
专利号:CN-105753852-B 优先权日:2016-03-26 标题 :Solvent-free Solid Phase Synthesis and Application of Microwave Digestion of Oxygen-, Sulfur- and Nitrogen-Containing Five-membered Heterocyclic azoles
专利号:CN-102653533-B 优先权日:2011-10-09 标 题 :A kind of total synthesis method of mangostin
专利号:CN-102653533-A 优先权日:2011-10-09 标题 :A kind of total synthesis method of mangostin (mangostin)
专利号:CN-106800539-B 优先权日:2016-12-30 标 题 :A kind of acotiamide hydrochloride intermediate and its synthesis technology and application
专利号:CN-106800539-A 优先权日:2016-12-30 标题:A kind of acotiamide hydrochloride intermediate and its synthesis process and application
[参考文献]: Oh H, Et Al. Asaronic Acid Attenuates Macrophage Activation Toward M1 Phenotype Through Inhibition Of Nf-κb Pathway And Jak-Stat Signaling In Glucose-Loaded Murine Macrophages. J Agric Food Chem. 2019;67(36):10069-10078.
合成参考文献
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