4-溴-2-硝基苯酚置于platinum On Activated Charcoal 氢氧化钾,氢气体系中,用 乙醇,乙酸乙酯 作为反应溶剂,化学反应生成 5-溴苯并恶唑-2-硫醇
参考文献:Regulatory Molecules For The 5-Ht3 Receptor Ion Channel Gating System
标题:Regulatory Molecules For The 5-Ht3 Receptor Ion Channel Gating System
摘要:Substituted Benzoxazole Derivatives Which Possess A Nitrogen Containing Heterocycle At C2 Are Selective Partial Agonists Of The 5-Ht3 Receptor. Alteration Of Substituents On The Benzoxazole Nucleus Affords Both Agonist-Like And Antagonist-Like Compounds,And Uniquely Modifies The Function Of The 5-Ht3 Receptor Ion Channel Gating System. Sar And Corroborative Computational Docking Study For These Partial Agonists Successfully Explained Structure And Function Of The 5-Ht3 Receptor. (C) 2007 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmc.2007.02.054