CAS: 3344-70-5; 1,12-Dibromododecane

该化合物是一种线性烷,其化学配方为C12H24BR2,其特点是多德内链中第一和第二个碳原子中存在两个溴原子,在室温下,这种化合物无色可粉黄,在室内温度下不见黄色液体,在水中不溶,但在乙醇和乙醇等有机溶剂中可溶解,具有相对高的沸点,因为其长的碳链和卤素原子的存在会增加分子的中间力. 1,12-二溴二烷主要用于有机合成,并在各种化学反应中用作试剂,包括交叉相撞反应和作为更复杂的分子的建筑块.其溴基子使该物质成为对烷的再活性和功能化研究中的有用化合物.然而,重要的是要谨慎地处理该物质,因为溴化化合物可能有害,并可能构成环境风险.在与该化学品合作时,应当遵循适当的安全议定书.

结构式图片

相似化合物

4101-68-2 4549-31-9 4549-32-0

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号5675-51-4 1,12-十二烷二醇 | CAS号3344-77-2 12-溴-1-十二烷醇 | CAS号5876-87-9 1,11-十二碳二烯 | CAS号73367-80-3 12-溴十二烷酸 | CAS号4543-66-2 癸二腈 | CAS号1731-79-9 十二烷二酸二甲酯 | CAS号4101-68-2 1,10-二溴癸烷 | CAS号20965-27-9 7-溴庚腈 | CAS号73120-52-2 1,12-dimethoxyd... | CAS号110-52-1 1,4-二溴丁烷 | CAS号110843-41-9 1,12-dinitrododecane | CAS号42236-50-0 1,12-二乙酰氧基十二烷 | CAS号506-13-8 16-羟基十六烷酸 | CAS号210237-15-3 dodec-11-enylph... | CAS号222832-70-4 1-bromo-12-(12-... | CAS号2536-36-9 ihda | CAS号88336-99-6 methyl 15-pheny... | CAS号7098-22-8 四十四烷 | CAS号505-54-4 十六烷二酸 | CAS号101122-64-9 triethyl-[12-(t...

合成工艺路线路线简述

    12-溴-1-十二烷醇置于氢溴酸体系中,用 溶剂黄146 用作溶剂,化学反应 18.0H,以67%的收率获得1,12-二溴十二烷
    参考文献:Synthesis Of Four N-Alkanes With Terminal Dipolar Substituents
    标题:Synthesis Of Four N-Alkanes With Terminal Dipolar Substituents
    摘要:
    Doi:10.1016/s0040-4020(01)89937-3

    海关参考信息

    专利信息


    专利号:US-7557099-B2
    优先权日:2004-03-01
    标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines
    发明人:HOWARD PHILIP WILSON; KANG GYOUNG-DONG
    权利人:SPIROGEN LTD
    摘要:Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R 2 and R 3 are independently selected from —H, â•?O, â•?CH 2 , —CN, —R, OR, halo, â•?CH—R, O—SO 2 —R, CO 2 R and COR; R 10 is a carbamate-based nitrogen protecting group; and R 11 is an oxygen protecting group.

    专利号:US-9782748-B2
    优先权日:2008-08-08
    标题:Synthesis of polymeric ionic liquids using a photochemical polymerization process
    发明人:ANDERSON JARED L
    权利人:UNIV TOLEDO
    摘要:Photo-initiated polymeric ionic liquids, methods of making and methods of using the same are disclosed. A preferred embodiment for making a photo-initiated polymeric ionic liquid (P-PIL) coated support, comprises: mixing at least one ionic liquid (IL) monomer with at least one photo-initiator; at least partially coating a support with the mixture; and exposing the coated support to UV light to form a photo-initiated polymeric ionic liquid (P-PIL) coated support.

    专利号:US-5405596-A
    优先权日:1993-06-29
    标题:Synthesis of crystalline ZSM-23
    发明人:MOINI AHMAD; SCHMITT KIRK D
    权利人:MOBIL OIL CORP
    摘要:This invention relates to a new form of crystalline material identified as having the structure of ZSM-23, to a new and useful method for synthesizing said crystalline material and to use of said crystalline material prepared in accordance herewith as a catalyst for organic compound, e.g., hydrocarbon compound, conversion.

    专利号:EP-1636294-B1
    优先权日:2003-06-20
    标 题 :Synthesis method for a compound used to form a self-assembled monolayer, compound for forming a self-assembled monolayer, and layer structure for a semiconductor component
    发明人:EFFENBERGER FRANZ; SCHUETZ MARKUS; MAISCH STEFFEN; SEIFRITZ STEFFEN; SCHMID GUENTER; HALIK MARCUS; KLAUK HAGEN; ZSCHIESCHANG UTE; HOLBERG STEFAN
    权利人:QIMONDA AG
    摘要:The invention relates to a synthesis method for a compound used to form a self-assembled monolayer, especially a monolayer for a semiconductor component, said method being characterised in that: a) it comprises a first synthesis step wherein a terminal nucleophile substitution of the halogen with a group able to perform a Î -Î interaction, especially a group having at least one aromatic group (Ar), is carried out on a ?-halogen-alk-1-ene (I), and b) the product of the first synthesis step is hydrolysed in a second synthesis step. The invention also relates to compounds for forming a self-assembled monolayer, and a layer structure. The inventive synthesis method thus enables compounds to be efficiently produced, generating a high yield and simple cleaning requirements.

    专利号:US-2009111737-A1
    优先权日:1999-05-24
    标题:Novel antibacterial agents
    发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

    专利号:CN-113548950-B
    优先权日:2021-08-05
    标 题 :Ultrasound-assisted Aqueous Phase Synthesis of Benzoin and Its Derivatives
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    主要参考文献

    [参考文献]: María Cordero-Vaca, Et Al. Automated Direct-Immersion Solid-Phase Microextraction Using Crosslinked Polymeric Ionic Liquid Sorbent Coatings For The Determination Of Water Pollutants By Gas Chromatography. Anal Bioanal Chem. 2015 Jun;407(16):4615-27.

    合成参考文献


    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1302.
    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1272.
    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1282.
    摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#05707
    参考文献:10.1107/s1600536810040134
    摘要:Dardouri R, Ouazzani Chahdi F, Saffon N, Essassi EM, Ng SW. 3-(12-Bromododecyl)-1,5-dimethyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione. Acta Crystallogr E Struct Rep Online. 2010 Oct 13;66(11):o2805. doi: 10.1107/s1600536810040134.
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