12-溴-1-十二烷醇置于氢溴酸体系中,用 溶剂黄146 用作溶剂,化学反应 18.0H,以67%的收率获得1,12-二溴十二烷 参考文献:Synthesis Of Four N-Alkanes With Terminal Dipolar Substituents 标题:Synthesis Of Four N-Alkanes With Terminal Dipolar Substituents 摘要: Doi:10.1016/s0040-4020(01)89937-3
专利号:US-7557099-B2 优先权日:2004-03-01 标题 :Pyrrolobenzodiazepines as key intermediates in the synthesis of dimeric cytotoxic pyrrolobenzodiazepines 发明人:HOWARD PHILIP WILSON; KANG GYOUNG-DONG 权利人:SPIROGEN LTD 摘要:Compounds and a method of synthesis of compounds of formula (Ia) or (Ib): and salts, solvates, and chemically protected forms thereof, wherein the dotted lines indicate the optional presence of a double bond between C1 and C2 or C2 and C3; R 2 and R 3 are independently selected from —H, â•?O, â•?CH 2 , —CN, —R, OR, halo, â•?CH—R, O—SO 2 —R, CO 2 R and COR; R 10 is a carbamate-based nitrogen protecting group; and R 11 is an oxygen protecting group.
专利号:US-9782748-B2 优先权日:2008-08-08 标题:Synthesis of polymeric ionic liquids using a photochemical polymerization process 发明人:ANDERSON JARED L 权利人:UNIV TOLEDO 摘要:Photo-initiated polymeric ionic liquids, methods of making and methods of using the same are disclosed. A preferred embodiment for making a photo-initiated polymeric ionic liquid (P-PIL) coated support, comprises: mixing at least one ionic liquid (IL) monomer with at least one photo-initiator; at least partially coating a support with the mixture; and exposing the coated support to UV light to form a photo-initiated polymeric ionic liquid (P-PIL) coated support.
专利号:US-5405596-A 优先权日:1993-06-29 标题:Synthesis of crystalline ZSM-23 发明人:MOINI AHMAD; SCHMITT KIRK D 权利人:MOBIL OIL CORP 摘要:This invention relates to a new form of crystalline material identified as having the structure of ZSM-23, to a new and useful method for synthesizing said crystalline material and to use of said crystalline material prepared in accordance herewith as a catalyst for organic compound, e.g., hydrocarbon compound, conversion.
专利号:EP-1636294-B1 优先权日:2003-06-20 标 题 :Synthesis method for a compound used to form a self-assembled monolayer, compound for forming a self-assembled monolayer, and layer structure for a semiconductor component 发明人:EFFENBERGER FRANZ; SCHUETZ MARKUS; MAISCH STEFFEN; SEIFRITZ STEFFEN; SCHMID GUENTER; HALIK MARCUS; KLAUK HAGEN; ZSCHIESCHANG UTE; HOLBERG STEFAN 权利人:QIMONDA AG 摘要:The invention relates to a synthesis method for a compound used to form a self-assembled monolayer, especially a monolayer for a semiconductor component, said method being characterised in that: a) it comprises a first synthesis step wherein a terminal nucleophile substitution of the halogen with a group able to perform a Î -Î interaction, especially a group having at least one aromatic group (Ar), is carried out on a ?-halogen-alk-1-ene (I), and b) the product of the first synthesis step is hydrolysed in a second synthesis step. The invention also relates to compounds for forming a self-assembled monolayer, and a layer structure. The inventive synthesis method thus enables compounds to be efficiently produced, generating a high yield and simple cleaning requirements.
专利号:US-2009111737-A1 优先权日:1999-05-24 标题:Novel antibacterial agents 发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES 权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES 摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.
专利号:CN-113548950-B 优先权日:2021-08-05 标 题 :Ultrasound-assisted Aqueous Phase Synthesis of Benzoin and Its Derivatives
[参考文献]: María Cordero-Vaca, Et Al. Automated Direct-Immersion Solid-Phase Microextraction Using Crosslinked Polymeric Ionic Liquid Sorbent Coatings For The Determination Of Water Pollutants By Gas Chromatography. Anal Bioanal Chem. 2015 Jun;407(16):4615-27.
合成参考文献
摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1302. 摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1272. 摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1282. 摘要:U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals., NX#05707 参考文献:10.1107/s1600536810040134 摘要:Dardouri R, Ouazzani Chahdi F, Saffon N, Essassi EM, Ng SW. 3-(12-Bromododecyl)-1,5-dimethyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione. Acta Crystallogr E Struct Rep Online. 2010 Oct 13;66(11):o2805. doi: 10.1107/s1600536810040134.