CAS: 1934-16-3; 3,7-Bis(Ethylamino)-2,8-Dimethylphenothiazin-5-Ium Chloride

该化合物是属于苯并呋喃类的一种化学化合物,其特点是含有硫和氮原子的三环结构,该化合物在3和7个位置上有两个乙基氨基组,在苯并氮核心2和8个位置上有两个甲基组,其独特性能有所增强.该化合物通常作为氯化盐遇到,它增加了极地溶剂中的溶解性.四硝基铵结构的存在具有解释性特征,使其在各种应用中有用,包括染色或生物研究中.该化合物可能展示生物活动,有可能影响细胞过程,并且对药理学研究感兴趣.其稳定性,溶解性和再活性可能受到周围的pH和溶剂环境的影响,使其在合成和应用化学环境下成为多种化合物.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

N1-ethyl-2-methyl-p-phenylenediamineN1-ethyl-2-methyl-p-phenylenediamine N-ethyl-2-methyl-4-nitroso-anilineN-ethyl-2-methyl-4-nitroso-aniline N-ethyl-N-nitroso-o-toluidineN-ethyl-N-nitroso-o-toluidine

合成工艺路线路线简述

    📜N-Ethyl-N-Nitroso-O-Toluidine置于盐酸体系中,化学反应生成新亚甲基蓝n
    参考文献:Weinberg,Chemische Berichte,1892,Vol. 25,P. 1611
    标题:Weinberg,Chemische Berichte,1892,Vol. 25,P. 1611

    海关参考信息

    专利信息


    专利号:US-2003131363-A1
    优先权日:2001-12-07
    标 题 :Heme-regulated eukaryotic initiation factor 2 alpha kinase knockout mice and methods for use
    发明人:CHEN JANE-JANE
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:The targeted disruption of the gene encoding the heme-regulated eIF2-kinase (HRI) in mice establishes that HRI, which is expressed predominantly in erythroid cells, regulates the synthesis of both alpha and beta globins in red blood cell precursors by inhibiting the general translation initiation factor eIF2. HRI is a physiological regulator of gene expression in the erythroid lineage and acts both as a sensor of heme and an effector controlling the initiation of translation. Accordingly regulation of HRI can be used to control proliferation of cells, especially cells of hematopoietic origin, using compositions and compounds identified using HRI deficient mice.

    专利号:US-2016144002-A1
    优先权日:1999-08-30
    标题:Sickled Erythrocytes and Progenitors Target Cytotoxics to Tumors
    发明人:TERMAN DAVID S
    权利人:TERMAN DAVID S
    摘要:The present invention provides therapeutic mammalian cells which synthesize and express SS hemoglobin and a tumoricidal transgene. They are produced by transduction of SS erythroid progenitors/erythroblasts using viral vectors comprising a tumoricidal transgene operatively linked to the coding region of SS β-globin promoter/enhancer. Such transduced SS erythroid cells differentiate into mature SSRBCs that exhibit sustained synthesis and expression of SS hemoglobin, a tumoricidal protein(s). Both mature and progenitor SS-cells carrying tumoricidal transgene(s) are capable of selectively localizing in tumor microenvironment, occluding tumor microvessels and inducing a tumoricidal response.

    专利号:CN-107983385-A
    优先权日:2017-11-28
    标 题:A kind of nickel base magnetic composite material and its synthesis method and application

    专利号:CN-107983385-B
    优先权日:2017-11-28
    标题:A kind of nickel-based magnetic composite material and its synthesis method and application

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