CAS: 171050-06-9; 3-Cyano-4-Fluorobenzoic Acid

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上下游产品

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📜3-溴-4-氟苯甲醛置于sodium Chlorite,Sodium Dihydrogenphosphate体系中,用 N-甲基吡咯烷酮,水,叔丁醇 用作溶剂,化学反应生成3-氰基-4-氟苯甲酸
参考文献: Novel Oxadiazole Compounds[fr] Composés Inédits D'Oxadiazole
标题: Novel Oxadiazole Compounds[fr] Composés Inédits D'Oxadiazole
摘要:新型噁二唑化合物,含有这种化合物的药物组合物以及将这些化合物或组合物用作治疗与调节s1P家族g蛋白偶联受体活性相关的疾病的激动剂或拮抗剂的用途被披露,特别是通过提供有益的免疫抑制作用.

专利信息

专利号:US-8507538-B2
优先权日:2009-11-13
标 题:Selective heterocyclic sphingosine 1 phosphate receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD
权利人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD; RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-9481659-B2
优先权日:2011-05-13
标 题 :Selective heterocyclic sphingosine 1 phosphate receptor modulators
发明人：BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD
权利人:BOEHM MARCUS F; MARTINBOROUGH ESTHER; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TAMIYA JUNKO; HUANG LIMING; YEAGER ADAM RICHARD; CELGENE INT II SÀRL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.