CAS: 160982-11-6; 3-(2-Bromoacetyl)-5-Chlorothiophene-2-Sulfonamide

相似化合物

160982-10-5 174139-67-4 154127-28-3

上下游产品

3-乙酰基-5-氯噻吩-2-磺酰胺 3-Acetyl-5-Chloro-2-Thiophenesulfonamide 160982-10-5
3-Acetyl-5-Chloro-2-Thiophenesulfenamide

3-乙酰基-5-氯噻吩-2-磺酰胺置于硫酸,Pyridinium Hydrobromide Perbromide体系中,用 水,乙酸乙酯 用作溶剂,以72%的收率获得3-(溴乙酰基)-5-氯-2-噻吩磺酰胺
参考文献:Preparation Of Carbonic Anhydrase Inhibitors
标题:Preparation Of Carbonic Anhydrase Inhibitors
摘要:揭示了一种合成碳酸酐酶抑制剂的过程.

专利信息

专利号:US-5470973-A
优先权日:1994-10-03
标 题 :Synthesis of sulfonamide intermediates
发明人：HOFF ROMAN
权利人:ALCON LAB INC
摘要:Enantioselective syntheses of (S)-6-chloro-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-4-ol 1,1-dioxide and related compounds are described.

专利号:WO-9610573-A1
优先权日:1994-10-03
标 题:Enantioselective synthesis of sulfonamide intermediates

专利号:US-8344136-B2
优先权日:2008-06-16
标题:Process for the preparation of brinzolamide
发明人：FALCHI ALESSANDRO; DE LUCCHI OTTORINO; CASTELLIN ANDREA
权利人:PHF S A; FALCHI ALESSANDRO; DE LUCCHI OTTORINO; CASTELLIN ANDREA
摘要:The present invention relates to a process for the preparation of Brinzolamide, or 2H-thieno[3,2-e]-1,2-thiazin-6-sulfonamide, 4-(ethyl amino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-via intermediates 2,3-dihydro-4H-thieno[3,2-e]-1,2-thiazin-4-ones, 1,1-dioxide. Further objects of the present invention are the intermediates mentioned above and other intermediates of the synthesis.