CAS: 107-84-6; 1-Chloro-3-Methylbutane

上下游产品

1,3-二氯-3-甲基丁烷 1,3-Dichloro-3-Methylbutane 624-96-4

2-甲基丁烷 反应生成1-氯-3-甲基丁烷
参考文献:Aschan,Chemisches Zentralblatt,1918,Vol. 89,# Ii,P. 939
标题:Aschan,Chemisches Zentralblatt,1918,Vol. 89,# Ii,P. 939

专利信息

专利号:US-11639326-B2
优先权日:2017-04-06
标 题 :Continuous flow synthesis of ibuprofen
发明人：COLLINS NATHAN; MALERICH JEREMIAH; SZETO JUDY; KOZOCAS JOSEPH A
权利人:STANFORD RES INST INT
摘要:This disclosure generally relates to methods of making ibuprofen, naproxen, and derivatives thereof. This disclosure also generally relates to compounds made by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-3983177-A
优先权日:1971-06-24
标 题 :Process for the preparation of unsaturated ketones
发明人：GRARD CHARLES
权利人:RHONE POULENC SA
摘要:Ketones, which are intermediates in the synthesis of vitamin A or perfumes, and have the general formula: R2R3 ¦¦ CCH2CR6O (I) ANGLE ANGLE ANGLE ¦ PARALLEL R1--CH2CHCHC-CH2-C-C-R8 n¦¦¦ R4R5R7 wherein R1 is hydrogen or C1-10 hydrocarbon, R2 and R3 are hydrogen or C1-4 alkyl, R4 and R5 are hydrogen or together form a -CH2-CH2-C(CH3)2- group, R6 and R7 are hydrogen or C1-10 hydrocarbon, or together with the carbon atom to which they are joined form a hydrocarbon ring of up to 10 carbons, or ¦ R6-C-C-R8 ¦ PARALLEL R7O forms a hydrocarbon ring of up to 10 carbons joined through R6 and R8 or R7 and R8, R8 is hydrogen or C1-10 hydrocarbon and n is 0-6, are prepared by reacting an unsaturated halide of formula R2R3 ¦¦ CCH2CCH2X (II) ANGLE ANGLE ANGLE ¦ R1--CH2CHCHC n¦¦ R4R5 wherein X is halogen, with an enol ester of formula R6 ANGLE C=C-R8 (III) ¦ R7OOC-R9 wherein R9 is C1-20 hydrocarbon, in the presence of a metal catalyst.

专利号:US-4293497-A
优先权日:1977-12-29
标 题:Coupling reaction involving a grignard and allylic halide
发明人：CARDENAS CARLOS G; DIN ZIA U
权利人:SCM CORP
摘要:Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or allylic halide and then carrying out the coupling reaction by the addition on the Grignard reagent to the allylic halide, said reaction being characterized by the displacement at the gamma position (relative to the halide) of the allylic halide with R of the Grignard reagent, migration of the allylic double bond in the direction of the halogen atom and loss of halogen. The present invention also resides in the discovery of certain novel procedures for the synthesis of Vitamin E. Specific embodiments of this aspect of the invention reside in the syntheses of 6,7-dehydrophytol, 10,11-dihydrofarnesene, phytone, hexahydropseudoionone, and related compounds as precursors for Vitamin E.

专利号:US-4292454-A
优先权日:1977-12-29
标题 :Coupling reaction involving a Grignard and allylic halide
发明人：CARDENAS CARLOS G; UD DIN ZIA
权利人:SCM CORP
摘要:Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or allylic halide and then carrying out the coupling reaction by the addition of the Grignard reagent to the allylic halide, said reaction being characterized by the displacement at the gamma position (relative to the halide) of the allylic halide with R of the Grignard reagent, migration of the allylic double bond in the direction of the halogen atom and loss of halogen. The present invention also resides in the discovery of certain novel procedures for the synthesis of Vitamin E. Specific embodiments of this aspect of the invention reside in the syntheses of 6,7-dehydrophytol, 10,11-dihydrofarnesene, phytone, hexahydropseudoionone, and related compounds as precursors for Vitamin E.

专利号:US-4292459-A
优先权日:1975-07-16
标 题:Coupling reaction involving a Grignard and allylic halide
发明人：CARDENAS CARLOS G; UD DIN ZIA
权利人:SCM CORP
摘要:Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or allylic halide and then carrying out the coupling reaction by the addition of the Grignard reagent to the allylic halide, said reaction being characterized by the displacement at the gamma position (relative to the halide) of the allylic halide with R of the Grignard reagent, migration of the allylic double bond in the direction of the halogen atom and loss of halogen. The present invention also resides in the discovery of certain novel procedures for the synthesis of Vitamin E. Specific embodiments of this aspect of the invention reside in the syntheses of 6,7-dehydrophytol, 10,11-dihydrofarnesene, phytone, hexahydropseudoionone, and related compounds as precursors for Vitamin E.

专利号:US-4221742-A
优先权日:1977-12-29
标题:Coupling reaction involving a Grignard and allylic halide
发明人：CARDENAS CARLOS G; DIN ZIA U
权利人:SCM CORP
摘要:Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or allylic halide and then carrying out the coupling reaction by the addition of the Grignard reagent to the allylic halide, said reaction being characterized by the displacement at the gamma position (relative to the halide) of the allylic halide with R of the Grignard reagent, migration of the allylic double bond in the direction of the halogen atom and loss of halogen. The present invention also resides in the discovery of certain novel procedures for the synthesis of Vitamin E. Specific embodiments of this aspect of the invention reside in the syntheses of 6,7-dehydrophytol, 10,11-dihydrofarnesene, phytone, hexahydropseudoionone, and related compounds as precursors for Vitamin E.