148-24-3 = 83-73-8 反应条件:1.1 Reagents: Iodate(1-),Dichloro-,Potassium Solvents: Water 标题:Aromatic Iodination In Aqueous Solution. A New Lease Of Life For Aqueous Potassium Dichloroiodate 作者:Garden,S. J.; Et Al 参考文献:Tetrahedron Letters 日期:2001 卷标:42(11) 页码:2089-2092]
7385-89-9 = 83-73-8 反应条件:1.1 Reagents: Triethylamine2.1 Reagents: 1,3-Diiodo-5,5-Dimethyl-2,4-Imidazolidinedione Catalysts: Benzyltriethylammonium Chloride Solvents: Water; 12 H,Rt2.2 Reagents: Silica 标题:Direct Phase-Transition Catalysed Monohalogenation Of 8-Amidoquinolines At C5 Position In Water 作者:He,Xin; Et Al 参考文献:Chemistryselect 日期:2021 卷标:6(21) 页码:5191-5194]
148-24-3 = 83-73-8 反应条件:1.1 Reagents: Hydrochloric Acid,Sodium Iodide,Sodium Chlorite Solvents: Methanol,Water; 40 Min,Rt 标题:Mild And Efficient Iodination Of Aromatic And Heterocyclic Compounds With The Naclo2/nai/HCL System 作者:Lista,Liliana; Et Al 参考文献:Tetrahedron 日期:2008 卷标:64(1) 页码:234-239]
148-24-3 = 83-73-8 反应条件:1.1 Reagents: Iodate(1-),Dichloro-,Potassium 标题:Potassium Dichloroiodate 作者:Lima,Edson L. S.; Et Al 参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2003 卷标:1 页码:1-2]
= 83-73-8 反应条件:1.1 Reagents: 1,3-Diiodo-5,5-Dimethyl-2,4-Imidazolidinedione Catalysts: Benzyltriethylammonium Chloride Solvents: Water; 12 H,Rt1.2 Reagents: Silica 标题:Direct Phase-Transition Catalysed Monohalogenation Of 8-Amidoquinolines At C5 Position In Water 作者:He,Xin; Et Al 参考文献:Chemistryselect 日期:2021 卷标:6(21) 页码:5191-5194
专利号:US-9382288-B2 优先权日:2010-10-06 标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action 发明人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO 权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG 摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).
专利号:WO-2012149093-A1 优先权日:2011-04-26 标 题 :2-guanidino-4-oxo-imidazoline derivatives as antimalarial agents, synthesis and methods of use thereof 发明人:LIN AI J; LIU XIANJUN; KOZAR MICHAEL P; O'NEIL MICHAEL T 权利人:US OF AMERICA AS REPRESENTED BY THE SECRETARY OF ARMY; LIN AI J; LIU XIANJUN; KOZAR MICHAEL P; O'NEIL MICHAEL T 摘要:The present invention relates to new 2-guanidino-4-oxo-imidazoline derivatives (deoxo-IZ), methods of making these compounds, compositions containing the same, and methods of using the same to prevent, treat, or inhibit malaria in a subject.
专利号:US-2006287257-A1 优先权日:2005-06-20 标 题 :Pharmaceutical compositions to treat diseases caused by mycobacterium 发明人:STOCKEL RICHARD F 权利人:STOCKEL RICHARD F 摘要:The invention teaches the synthesis of pharmaceutical composition and methods of synthesis to treat people and animals infected with a pathogenic mycobacterium. In particular the compositions of this invention are suitable for the treatment of tuberculosis, malaria, and other infections diseases caused by mycobacterium.
专利号:US-9907753-B2 优先权日:2010-03-19 标 题 :Lipid vesicle compositions and methods of use 发明人:IRVINE DARRELL J; MOON JAEHYUN 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
专利号:WO-2012149097-A2 优先权日:2011-04-26 标 题 :Guanidylimidazole and guanidylimidazoline derivatives as antimalarial agents, synthesis of and methods of use thereof
专利号:US-2007148246-A1 优先权日:2005-08-11 标题:Nucleic Acid-Based Matrixes 发明人:LUO DAN; LI YOUGEN 权利人:LUO DAN; LI YOUGEN 摘要:Various nucleic acid-based matrixes are provided, comprising nucleic acid monomers as building blocks, as well as nucleic acids encoding proteins, so as to produce novel biomaterials. Methods of utilizing such biomaterials include delivery of biologically active agents, cell and tissue culture, and cell-free protein synthesis.
1: Fisher AK, Walter FG, Szabo S. Iodoquinol associated seizures and radiopacity. J Toxicol Clin Toxicol. 1993;31(1):113-20. doi: 10.1128/AAC.05125-11. Epub 2011 Oct 24. 5: Chan FT, Guan MX, Mackenzie AM, Diaz-Mitoma F. Susceptibility testing of Dientamoeba fragilis ATCC 30948 with iodoquinol, paromomycin, tetracycline, and metronidazole. Antimicrob Agents Chemother. 1994 May;38(5):1157-60. 6: Mackey-Lawrence NM, Petri WA Jr. Amoebic dysentery. BMJ Clin Evid. 2011 Jan 13;2011. pii: 0918. Review.
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