N,N-二甲基丙烯酰胺置于sodium Tetrahydroborate,Iron(Iii) Trifluoromethanesulfonate,乙醇体系中,化学反应 6.0H,反应生成 N,N-二甲基丙酰胺 参考文献:Iron-Catalysed,General And Operationally Simple Formal Hydrogenation Using Fe(Otf)3 And Nabh4 标题:Iron-Catalysed,General And Operationally Simple Formal Hydrogenation Using Fe(Otf)3 And Nabh4 摘要:已开发出一种操作简单且环境友好的正规氢化方案,使用高丰度的铁(iii)盐和廉价,台面稳定,化学计量还原剂nabh4,在乙醇中,在常温下进行. DOI:10.1039/c4Ob00945B
专利号:US-8252928-B2 优先权日:2008-09-16 标题:Processes for the synthesis of five and six membered heterocyclic rings 发明人:WANG PETER X; JIANG TAO; BERBERICH DAVID W 权利人:WANG PETER X; JIANG TAO; BERBERICH DAVID W; MALLINCKRODT LLC 摘要:The present invention provides processes for the synthesis of five and six membered rings. In particular, the present invention provides processes for the synthesis of five and six membered rings in alkaloids.
专利号:US-8742028-B2 优先权日:2009-05-06 标 题:Solid support for Fmoc-solid phase synthesis of peptide acids 发明人:SRIVASTAVA KRIPA S; DAVIS MATTHEW R 权利人:SRIVASTAVA KRIPA S; DAVIS MATTHEW R; MALLINCKRODT LLC 摘要:The present invention provides a solid support for Fmoc-solid phase synthesis of peptides. In particular, the solid supports of the invention may be utilized to produce peptide acids.
专利号:US-8420848-B2 优先权日:2009-01-09 标题:Process for the synthesis of beta glycerol phosphate 发明人:KULKARNI YASHWANT 权利人:KULKARNI YASHWANT; SIGMA ALDRICH CO LLC 摘要:The present invention provides methods for the preparation of beta glycerol phosphate and its salts. In particular, the invention provides efficient methods for the synthesis of beta glycerol phosphate of high purity.
专利号:WO-9804535-A1 优先权日:1996-07-26 标 题 :A practical synthesis of benzoxazinones useful as hiv reverse transcriptase inhibitors 发明人:PIERCE MICHAEL ERNEST; RADESCA LILIAN ALICIA 权利人:DU PONT MERCK PHARMA 摘要:The present invention describes novel methods for the synthesis of benzoxazinone compounds which are useful as human immunodeficiency virus (HIV) reverse transcriptase inhibitors. The benzoxazinone of formula (VI-a) is particularly effective in the treatment of HIV.
专利号:WO-2011011342-A9 优先权日:2009-07-20 标题:Synthesis of desmopressin 发明人:SRIVASTAVA KRIPA S 权利人:MALLINCKRODT INC; SRIVASTAVA KRIPA S 摘要:The present invention provides a process for the production of desmopressin. In particular, the process provides a process for solid phase synthesis of desmopressin using cyclization of the peptide on the resin.
专利号:US-3742080-A 优先权日:1969-04-11 标 题 :Rhodium based catalysts for the synthesis of 1,4-dienes 发明人:SU A 权利人:DU PONT 摘要:Improved catalysts are provided for the synthesis of 1,4-dienes from Alpha -monoolefins and conjugated dienes. The catalysts are rhodium (III) salts in combination with amides, phosphoramides, phosphine oxides, or water. The improved catalysts allow control of the trans-cis ratio of the 1,4-diene formed and are operable at useful rates in a wide range of solvent systems, both protonic and aprotic.
[参考文献]: Yasuhiro Umebayashi, Et Al. Conformation Of Solvent N,N-Dimethylpropionamide In The Coordination Sphere Of The Zinc(Ii) Ion Studied By Raman Spectroscopy And Dft Calculations. J Phys Chem A. 2005 Jun 2;109(21):4862-8. [参考文献]: Yusuke Asakura, Et Al. Topotactic Conversion Of β-Helix-Layered Silicate Into Ast-Type Zeolite Through Successive Interlayer Modifications. Chemistry. 2014 Feb 10;20(7):1893-900.
合成参考文献
摘要:Liang, Y.; Wen, Z.; Cabrera, M.; Howlader, A. H.; Wnuk, S. F., Science of Synthesis Knowledge Updates, (2020) 1, 200. 摘要:Shang, Y.; Ren, Y.; Su, W., Science of Synthesis: Special Topics, (2022) 1, 224. 摘要:American Industrial Hygiene Association Journal., 32(539), 1971 [] 摘要:de Figueiredo, R. M., Science of Synthesis: Knowledge Updates, (2024) 2, 332. 摘要:Tang, R.-Y., Science of Synthesis: Knowledge Updates, (2024) 1, 397.