CAS: 621-70-5; Propane-1,2,3-Triyl Trihexanoate

该化合物是一种化学化合物,被归类为三甘蓝酸,产自甘蓝和三碳酸(又称十氮酸)的分子,在室内温度下,色素无色可粉黄,以其低粘度和温和味闻名,在有机溶剂中可溶解,但水溶性有限,该化合物主要用于食品工业,作为乳化剂和稳定剂,以及用于化妆品和药品,以利其湿润特性,承认它有能力增强产品的质质质和口服,使其在配方中具有价值,此外,由于其生物相容性,它有可能被用于生产生物柴油,并因其生物相容性而成为药物运载系统的载体,安全数据表明,它一般被视为在食品和化妆品应用中可以安全使用,尽管与所有化学品一样,应该以适当的防范措施加以处理.

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上下游产品

CAS号56-81-5 甘油 | CAS号142-62-1 正己酸 | CAS号107-87-9 2-戊酮 | CAS号29752-80-5 N,N-bis(2-hydro... | CAS号10032-02-7 己酸香叶酯 | CAS号142-62-1 正己酸

合成工艺路线路线简述

    📜甘油,己酸置于glucose-Diphenylaminium Tosylate-Derived Carbon Solid Acid (Gdtcsa)体系中,用 正庚烷 作为反应溶剂,化学反应 18.0H,以93%的收率获得产物三己精
    参考文献:The Carbon Material Functionalized With Nh2+ And So3H Groups Catalyzed Esterification With High Activity And Selectivity
    标题:The Carbon Material Functionalized With Nh2+ And So3H Groups Catalyzed Esterification With High Activity And Selectivity
    摘要:一个新型碳材料被方便地制备出来,可以催化酯化反应,具有高反应活性和选择性.
    DOI:10.1039/c4Gc01395F

    海关参考信息

    专利信息


    专利号:US-5434278-A
    优先权日:1989-09-20
    标题:Synthesis of acetoglyceride fats
    发明人:PELLOSO TURIDDU A; RODEN ALLAN D; BOLDT GILBERT L
    权利人:NABISCO INC
    摘要:Acetoglycerides are prepared in a solventless, single phase interesterification between triacetin and triglycerides bearing long C 16 to C 22 fatty acid residues by adding triglycerides bearing saturated C 3 to C 10 acid residues to the reaction mixture. The long acid residues may be hydrogenated before or after interesterification. In one embodiment, the C 3 to C 10 triglycerides are tripropionin, tributyrin, or mixtures of these; in another, these are triglycerides bearing C 8 to C 10 acid residues; and in a third, these are a mixture of tripropionin and/or tributyrin and C 8 to C 10 triglycerides. In preferred embodiments, the molar ratio of C 16 to C 22 triglycerides to triacetin and C 3 to C 10 triglycerides varies between 1:1 and 1:15, more narrowly between 1:3 and 1:12, and high temperatures are employed. The process diminishes catalyst use, obviates the need for high shear mixing, shortens reaction times, and simplifies purification steps.

    专利号:EP-0682689-A4
    优先权日:1993-02-03
    标 题 :SYNTHESIS OF ACETOGLYCERIDE FATS.

    专利号:EP-0682689-A1
    优先权日:1993-02-03
    标 题 :Synthesis of acetoglyceride fats

    专利号:WO-9418290-A1
    优先权日:1993-02-03
    标 题:Synthesis of acetoglyceride fats

    专利号:US-5391494-A
    优先权日:1988-12-09
    标题 :Process for selectively producing optically active 1-derivatized-2-diol using lipase CES and triglyceride
    发明人:MIYAZAWA KAZUTOSHI; YOSHIDA NAOYUKI
    权利人:CHISSO CORP
    摘要:This invention provides optically active compounds which are starting materials of physiologically active substances, functional materials and the like, and the compounds are represented by the general formula (I): (I) wherein R1 is hydrogen or alkanoyl of 2-20 carbon atoms, R2 is alkyl of 1-40 carbon atoms, alkenyl of 1-40 carbon atoms, or alkynyl of 1-40 carbon atoms in which the alkyl, alkenyl or alkynyl moiety is possible to have phenyl, cyclohexyl, pyridyl, pyrimidyl, pyridadyl, pyrazyl, dioxyl, bicyclooctyl, or a substituent thereof, or halogen, cyanogen, oxygen, nitrogen, silicon or sulfur, and X is a protective group removable by a chemical method of organic synthesis and C* is an asymmetric carbon.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Jose A, Chaitanya MVNL, Kannan E, Madhunapantula SV. Tricaproin Isolated From Simarouba glauca Inhibits the Growth of Human Colorectal Carcinoma Cell Lines by Targeting Class-1 Histone Deacetylases. Front Pharmacol. 2018 Mar 12;9:127. doi: 10.3389/fphar.2018.00127.
    2: Ogawara KI, Fukuoka Y, Yoshizawa Y, Kimura T, Higaki K. Development of Safe and Potent Oil-in-Water Emulsion of Paclitaxel to Treat Peritoneal Dissemination. J Pharm Sci. 2017 Apr;106(4):1143-1148. doi: 10.1016/j.xphs.2016.12.029. Epub 2017 Jan 4. 174(1):339-51. doi: 10.1007/s12010-014-1063-3. Epub 2014 Jul 27. 57(21):10466-70. doi: 10.1021/jf902816e. 25(1):147-57. doi: 10.1007/s11095-007-9412-3. Epub 2007 Aug 18. 60(2):89-94. 89(5):451-7. doi: 10.1016/s1389-1723(00)89095-7. 32(4):285-9. doi: 10.1046/j.1365-2362.2002.00959.x. 130(8):2009-15. doi: 10.1093/jn/130.8.2009. 240(2):195-207. doi: 10.1016/0009-8981(95)06142-0. 1169(2):156-64. doi: 10.1016/0005-2760(93)90200-s. 119(4):581-5. doi: 10.1093/jn/119.4.581. 60(3):525-38. doi: 10.1079/bjn19880125. 116(6):944-56. doi: 10.1093/jn/116.6.944. 27(2):162-71. French. doi: 10.1159/000176636. influence du niveau d'alimentation antérieur [Effect on energy and nitrogen balances of replacing part of the tallow in a milk replacer for preruminant calves by tricaproin or coconut oil: effect of previous feeding level]. Reprod Nutr Dev. 1983;23(3):587-97. French. 44(5):353-354. doi: 10.4315/0362-028X-44.5.353. 49(6):924-30. Russian. 49(4):259-63. doi: 10.1007/BF02582589. 20(1):16-22.

    合成参考文献


    参考文献:10.1046/j.1365-2362.2002.00959.x
    摘要:Wanten GJ, Janssen FP, Naber AH. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. Eur J Clin Invest. 2002 Apr;32(4):285–9. doi: 10.1046/j.1365-2362.2002.00959.x.
    参考文献:10.1096/fasebj.11.1.9034165
    摘要:Ghosh S, Strum JC, Bell RM. Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling. FASEB J. 1997 Jan;11(1):45–50. doi: 10.1096/fasebj.11.1.9034165.
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