CAS: 520-42-3; Asebogenin

上下游产品

3-(p-hydroxyphenyl)propiononitrile 2,2,2-trichloro-1-(2,4-dihydroxy-6-methoxy-phenyl)-ethanone 2',4,6'-triisopropyloxy-4'-methoxydihydr°Chalcone 2',4,6'-trihydroxy-4'-methoxydihydr°Chalcone 2'-O-β-D-glucopyranoside3-(4-acetoxy-phenyl)-1-(2,6-diacetoxy-4-methoxy-phenyl)-propan-1-one

📜Phloridizin置于盐酸,二异丙胺体系中,用 1,4-二氧六环,甲醇 作为反应溶剂,化学反应 1.5H,反应生成 4'-O-甲基根皮素
参考文献:Dihydrochalcones: Evaluation As Novel Radical Scavenging Antioxidants
标题:Dihydrochalcones: Evaluation As Novel Radical Scavenging Antioxidants
摘要:Dihydrochalcones Are A Family Of Bicyclic Flavonoids,Defined By The Presence Of Two Benzene Rings Joined By A Saturated Three Carbon Bridge. In The Present Study,We Systematically Examined The Antioxidant Activities Of Dihydrochalcones Against The Stable Free Radical (1,1-Diphenyl-2-Picrylhydrazyl) And Lipid Peroxidation In The Erythrocyte Membrane. All Dihydrochalcones Exhibited Higher Antioxidant Activities Than The Corresponding Flavanones. The H-1 NMR Analysis Indicated That The Active Dihydrochalcone Has A Time-Averaged Conformation In Which The Aromatic A Ring Is Orthogonal To The Carbonyl Group,While The Inactive Dihydrochalcone Such As 2'-O-Methyl-Phloretin Has A Strongly Hydrogen-Bonded Phenolic Hydroxyl Group,Suggestive Of A Coplanar Conformation. A Hydroxyl Group At The 2'-Position Of The Dihydrochalcone A Ring,Newly Formed By Reduction Of The Flavanone C Ring,Is An Essential Pharmacophore For Its Radical Scavenging Potential.
DOI:10.1021/jf0341060