CAS: 467-36-7; 5-Cyclohex-2-En-1-Yl-5-Prop-2-Enyl-2-Sulfanylidene-1,3-Diazinane-4,6-Dione

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    合成工艺路线路线简述

      📜硫脲,Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 硫烯比妥
      参考文献:Abe,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1955,Vol. 75,P. 885
      标题:Abe,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1955,Vol. 75,P. 885

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      专利信息


      专利号:US-2007275962-A1
      优先权日:2003-09-10
      标 题:Heterobicyclic Compounds as Pharmaceutically Active Agents
      发明人:KOUL ANIL; KLEBL BERT; MULLER GERHARD; MISSIO ANDREA; SCHWAB WILFRIED; HAFENBRADL DORIS; NEUMANN LARS; SOMMER MARC-NICOLA; MULLER STEFAN; HOPPE EDMUND; FREISLEBEN ACHIM; BACKES ALEXANDER; HARTUNG CHRISTIAN; FELBER BEATRICE; ZECH BIRGIT; ENGKVIST OLA; KERI GYORGY; ORFI LASZLO; BANHEGYI PETER; GREFF ZOLTAN; HORVATH ZOLTAN; VARGA ZOLTAN; MARKO PETER; PATO JANOS; SZABADKAI ISTVAN; SZEKELYHID ZSOLT; WACZEK FRIGYES
      权利人:GPC BIOTECH AG
      摘要:Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

      专利号:US-11040939-B1
      优先权日:2020-06-23
      标 题 :N-transfer reagent and method for preparing the same and its application
      发明人:CHOU HO-HSUAN; LU GUAN-HAN; HSUEH HSIAO-CHIN; HUANG TZU-CHIA
      权利人:UNIV NAT CHENG KUNG
      摘要:Provided are a novel N-transfer reagent and a method for preparing the same and its application. The N-transfer reagent is represented by the following Formula (I): n n n n n n n n n n The various novel N-transfer reagents of the present invention can be quickly prepared by employing different nitrobenzene precursors. The N-transfer reagents can directly convert a variety of amino compounds into diazo compounds under mild conditions. Particularly, the N-transfer reagents can facilitate the synthesis of the diazo compounds. The application of synthesizing diazo compounds of the present invention can greatly decrease the difficulty in operation, increase the safety during experiments, reduce the cost of production and the environmental pollution, and enhance the industrial value of diazo compounds.

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      合成参考文献


      摘要:British Journal of Pharmacology and Chemotherapy., 1(215), 1946
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