CAS: 26774-88-9; (R)-2-Amino-2-(Cyclohexa-1,4-Dien-1-yl)Acetic Acid

相似化合物

7559-04-8 1128-13-8 20763-30-8

上下游产品

CAS号54855-97-9 (R)-2-(cyclohex... | CAS号20763-30-8 (2R)-氨基(环己-1,4-... | CAS号57872-59-0 b°C-2,5-dihydro...

(R)-α-Ureido-1,4-Cyclohexadien-1-Yl-Essigsaeure置于氢氧化钾,Sodium Hypochlorite,溶剂黄146,Sodium Nitrite体系中,化学反应生成(R)-(-)-2-(2,5-二氢苯基)甘氨酸
参考文献:Libassi,G. Et Al.,Gazzetta Chimica Italiana,1977,Vol. 107,P. 253-255
标题:Libassi,G. Et Al.,Gazzetta Chimica Italiana,1977,Vol. 107,P. 253-255

专利信息

专利号:US-2018222848-A1
优先权日:2015-08-04
标 题:Salt of Dihydrophenylglycine Methyl Ester
发明人：VAN DER DOES THOMAS; MOODY HAROLD MONRO; LI WEIDONG
权利人:DSM SINOCHEM PHARM NL BV
摘要:The present invention relates to the hemi sulfuric acid salt of methyl (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetate, also trivially referred to as the hemi sulfuric acid salt of D-dihydrophenylglycine methyl ester, to a method for the preparation of said salt and to the use of said salt in the enzymatic synthesis of antibiotics.

专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:US-2025084410-A1
优先权日:2015-01-12
标 题:Incorporation of unnatural nucleotides and methods thereof
发明人：PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
权利人:SYNTHORX INC
摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.

专利号:US-2018371021-A1
优先权日:2017-05-11
标 题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:US-6060268-A
优先权日:1995-07-18
标题:Penicillin G acylase immobilized with a crosslinked mixture of gelled gelatin and amino polymer
发明人：DE VROOM ERIK
权利人:GIST BROCADES BV
摘要:PCT No. PCT/EP96/03253 Sec. 371 Date Jan. 15, 1998 Sec. 102(e) Date Jan. 15, 1998 PCT Filed Jul. 16, 1996 PCT Pub. No. WO97/04086 PCT Pub. Date Feb. 6, 1997Penicillin G acylase is immobilized by covalent bonding to a crosslinked mixture of a gelled gelling agent such as gelatin and a polymer containing free amino groups such as alginate amine, chitosan or polyethylene imine. The immobilized penicillin G acylase provides a higher synthesis/hydrolysis ratio as compared to immobilizing with other carriers when producing beta -lactam derivatives by a condensing reaction of an amino beta -lactam with an acylating agent. The acylating agent may be a derivative of D-phenylglycine, a derivative of D-p-hydroxyphenylglycine or a derivative of D-2,5-dihydro-phenylglycine. Examples of beta -lactam derivatives that can be produced are amoxycillin, ampicillin, cephaclor, cephadroxil, cephprozil, cephalexin and cephradine.

专利号:RU-2381273-C2
优先权日:2008-03-04
标 题 :Method for production of heterogeneous biocatalyst, biocatalyst based on hydrolase of alpha-aminoacid ethers and method for synthesis of aminobeta-lactam antibiotic under action of this biocatalyst