CAS: 1929-29-9; 3-(4-Methoxyphenyl)Propanoic Acid

上下游产品

CAS号830-09-1 4-甲氧基肉桂酸 | CAS号15823-04-8 3-(4-甲氧基苯基)丙酸甲酯 | CAS号201230-82-2 carbon monoxide | CAS号768-60-5 4-甲氧基苯乙炔 | CAS号104-92-7 对溴苯甲醚 | CAS号292638-85-8 丙烯酸甲酯 | CAS号24680-50-0 反式4-甲氧基肉桂醛 | CAS号943-89-5 反-4-甲氧基肉桂酸 | CAS号3984-22-3 2-乙烯基-1,3-二氧戊环 | CAS号51-67-2 酪胺 | CAS号501-97-3 对羟基苯丙酸 | CAS号20921-02-2 7-methoxy-3,4-d... | CAS号1857-57-4 3-(3-溴-4-甲氧基苯基)丙酸 | CAS号637-69-4 4-甲氧基苯乙烯 | CAS号25413-27-8 3-(4-甲氧基苯基)-丙酰胺 | CAS号24634-11-5 m-Anisoyl chlor... | CAS号299953-06-3 5-(4-甲氧基-苄基)-噻唑-2-基胺 | CAS号20401-88-1 3-(4-甲氧基苯基)丙醛 | CAS号24077-98-3 1H-Indene-1,2(3...

反式-4-甲氧基肉桂酸置于甲酸,Palladium Dichloride体系中,用 Sodium Hydroxide,异丙醇 用作溶剂,化学反应 0.05H,以81%的收率获得3-(4-甲氧基苯基)丙酸
参考文献:一种快速有效的微波辅助从苯甲醛在几分钟内合成取代的 3-苯基丙酸
标题:一种快速有效的微波辅助从苯甲醛在几分钟内合成取代的 3-苯基丙酸
摘要:通过苯甲醛 (2A-2F) 和丙二酸在乙酸和哌啶中以 77% 至 89% 的比例反应生成肉桂酸 (3A-3F),然后再将其合成,从而方便,廉价且有效地合成 3-苯基丙酸 (1A-1F)据报道,在微波辐射下,在甲酸和氢氧化钠水溶液的两相中用 Pdcl2 还原,利用 5 到 7 分钟的短反应时间以中等至高产率(69-86%)提供 1A-1F,这取决于甲氧基,亚甲二氧基,和羟基存在于苯环上.
Doi:10.1246/cl.2003.1186

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-4824532-A
优先权日:1987-01-09
标题:Process for the electrochemical synthesis of carboxylic acids
发明人：MOINGEON MARIE-ODILE; CHAUSSARD JACQUES; TROUPEL MICHEL; SABOUREAU CHRISTOPHE
权利人:AEROSPATIALE
摘要:The invention relates to a process for the electrosynthesis of carboxylic acids of general formula R-COOH in which R is an organic radical by the electrochemical reduction, in the presence of carbon dioxide, of organic compounds corresponding to the general formula R-Y in which R is the above-mentioned organic radical and Y is a hetero atom-containing radical, the hetero atom of the radical Y, chosen from the group consisting of oxygen, nitrogen, sulphur andphosphorus, being directly linked to a carbon atom of the radical R by a single covalent linkage. When the hetero atom is nitrogen or phosphorus, the radical Y is an ammonium or phosphonium radical respectively. The anode, which is consumed during the electrosynthesis, is made of a metal chosen from the group consisting of reducing metals and their alloys, preferably made of magnesium, aluminium or zinc. This process without catalyst is very simple to perform and enables a cell with a single compartment to be employed. The carboxylic acids are commonly employed in the chemical industry, especially as intermediates for the synthesis of pharmaceutical products or of products used in plant protection.

专利号:EP-0946478-B1
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehydes, ketones and hydroxamic acid compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to processes for the solid-phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-5446158-A
优先权日:1989-01-11
标题:Process for synthesis of FK-506 and tricarbonyl intermediates
发明人：JONES TODD K; MILLS SANDER G; ASKIN DAVID; REAMER ROBERT A; DESMOND RICHARD; TSCHAEN DAVID M; VOLANTE RALPH P; SHINKAI ICHIRO
权利人:MERCK & CO INC
摘要:A process is described for the total synthesis of the macrolide immunosuppressant, FK-506, and important tricarbonyl process intermediates thereof. The tricarbonyl intermediates can be produced by the mild oxidation of 2,3-dihydroxy carboxylate compounds containing olefin moieties.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-11746364-B2
优先权日:2018-01-17
标题 :Enzymatic synthesis of kavalactones and flavokavains
发明人：PLUSKAL TOMÃ S; Weng jing-ke
权利人:WHITEHEAD INST BIOMEDICAL RES
摘要:Disclosed are methods, compositions, proteins, nucleic acids, cells, vectors, compounds, reagents, and systems for the preparation of kavalactones, flavokavains, and kavalactone and flavokavain biosynthetic intermediates using enzymes expressed in heterologous host cells, such as microorganisms or plants, or using in vitro enzymatic reactions. This invention also provides for the expression of the enzymes by recombinant cell lines and vectors. Furthermore, the enzymes can be components of constructs such as fusion proteins. The kavalactones produced can be utilized to treat anxiety disorder, insomnia, and other psychological and neurological disorders. The flavokavains produced can be utilized to treat various cancers including colon, bladder, and breast cancers.