CAS: 1719-76-2; 1-Isopropylthiourea

该化合物是一种有机化合物,其特征是存在硫尿素功能组,由碳原子双壳组成,形成硫硫磺原子,并形成单壳,该化合物一般是白色的,白色的晶体固体,可溶于水和酒精等极地溶剂,具有硫尿亚的典型特性,包括能够参与各种化学反应,例如核毒替代和凝聚反应.N-(1-甲基乙基乙基)硫尿亚经常用于有机合成,并可作为其他化合物的再生剂.此外,该化合物在农业化学和药物中具有潜在用途.与许多硫尿衍生物一样,必须谨慎地处理这一化合物,同时顾及潜在的毒性和环境影响.在实验室环境中与该物质打交道时,应注意采取适当的安全措施.

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CAS号52599-24-3 丁丙硫脲 | CAS号2253-73-8 异硫氰酸异丙酯 | CAS号27248-16-4 isopropylammoni... | CAS号691-61-2 thi°Carbamic ac... | CAS号75-31-0 异丙胺 | CAS号100-41-4 乙苯 | CAS号64-17-5 乙醇 | CAS号7664-41-7 氨 | CAS号500-92-5 氯胍 | CAS号850877-62-2 2-B°C-5-(2-异丙基氨... | CAS号860344-59-8 4-[2-(propan-2-... | CAS号860344-61-2 3-[2-(propan-2-...

合成工艺路线路线简述

    📜异硫氰酸异丙酯置于氨体系中,化学反应生成1-异丙基-2-硫脲
    参考文献:取代5,5'-二苯基-2-硫代咪唑啉酮-4-酮作为cb1大麻素受体配体:合成和药理学评估.
    标题:取代5,5'-二苯基-2-硫代咪唑啉酮-4-酮作为cb1大麻素受体配体:合成和药理学评估.
    摘要:合成了一组30个取代的5,5'-二苯基-2-硫代氧杂咪唑啉-4-酮(硫代乙内酰脲)衍生物,并评估了它们对人cb(1)大麻素受体的亲和力.这些化合物衍生自先前描述的大麻素配体5,5'-二苯基咪唑烷-2,4-二酮(乙内酰脲).用硫取代氧会导致亲和力增加,而[[35] S] Gtpgammas实验所确定的功能(即反向激动作用)仍然不受影响.最后,为了评估可能影响巯基乙内酰脲亲和力的分子参数,对代表性的巯基乙内酰脲和乙内酰脲衍生物进行了分子静电势以及亲脂性计算.总之,5,5'-双-(4-碘苯基)-3-丁基-2-硫代氧杂咪唑啉丁-4-酮(31)和3-烯丙基-5,
    Doi:10.1021/jm049263K

    海关参考信息

    专利信息


    专利号:US-4627968-A
    优先权日:1984-09-10
    标 题 :Synthesis of crystalline aluminosilicate with alkylurea or alkylthiourea
    发明人：KAI TADASHI
    权利人:ASAHI CHEMICAL IND
    摘要:In the synthesis of a crystalline aluminosilicate by heating an aqueous mixture containing a silica source, an alumina source and an alkali metal source, at least one compound selected from lower alkylureas and lower alkylthioureas is permitted to co-exist with the mixture.

    专利号:CN-112250661-A
    优先权日:2020-11-18
    标题 :A kind of method for catalyzing synthesis of lactide

    专利号:WO-2005105813-A1
    优先权日:2004-04-28
    标 题 :Improved process for the manufacture of ceftriaxone sodium
    发明人：JAWEED MUKARRAM SIDDIQUI MOHAM; NAITHANI PANKAJ KUMAR; PUROHIT MANISH; POKALWAR RAJKUMAR UDHAVRAO
    权利人:WOCKHARDT LTD; JAWEED MUKARRAM SIDDIQUI MOHAM; NAITHANI PANKAJ KUMAR; PUROHIT MANISH; POKALWAR RAJKUMAR UDHAVRAO
    摘要:A process for the production of (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-2-syn­methoxyimino)acetamido]-3-[[2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3­yl)thio]methyl]-8-oxo-5-thia-l-azabicyclo[4.2.0]-oct-2-ene-2-carboxylic acid (Ceftriaxone acid) in water is discussed. The synthesis is effected by condensing (7R)-7-Amino-3­deacetoxy-3-[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-yl)thio]cephalosporanic acid (7-ACT) with 2-(2-chloroacetamido-4-thiazolyl)-2-syn-methoxyiminoacetyl chloride followed be deblocking amino function. Finally, (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-2-syn­methoxyimino)acetamido]-3-[[2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3­yl)thio]methyl]-8-oxo-5-thia-l-azabicyclo[4.2.0]-oct-2-ene-2-carboxylic acid (Ceftriaxone acid) is converted into Ceftriaxone disodium hemiheptahydrate in aqueous acetone using sodium-2-ethylhexanoate as sodium source. Isolation steps at every stage are quite short. The purity of the final product is obtained in more than 99 % by HPLC profile.

    专利号:CN-112250661-B
    优先权日:2020-11-18
    标题:A kind of method for catalyzing synthesis of lactide

    专利号:GB-2164326-A
    优先权日:1984-09-10
    标 题 :Process for synthesis of crystalline aluminosilicate

    专利号:CN-120647586-A
    优先权日:2024-03-15
    标题:An imidazolylsulfur reagent, a synthesis method thereof, and its application in the selective construction of glucosinolate compounds

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    合成参考文献


    摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 285.
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