CAS: 138124-32-0; (R,R)-(-)-N,N'-Bis(3,5-Di-Tertbutylsalicylidene)-1,2- Cyclohexanediaminomanganese(Iii) Chloride

该化合物是一家手性锰(III)销售综合体,在有机合成中广泛用作不对称催化剂,其硬性环己胺脊柱和受到严重阻碍的异丁基组在氧化条件下增强了对等选择性和稳定性.这一综合体对天花化,C-H功能化和动能解析反应特别有效,提供了高更替次数和选择性.氯化物对立体能提高了极溶剂的溶解性,促进了同质催化.其定义明确的结构和可预测的再活性使它成为制药和精美化学合成中立体控制变形器的宝贵工具.该综合体的空气稳定性和易于处理进一步有助于其在实验室和工业应用中的用途.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

manganese (II) acetate tetrahydrate (R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine sodium chloride =G87N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexane diamine+G2+'12'!J6

合成工艺路线路线简述

    专利信息


    专利号:US-6388083-B2
    优先权日:2000-07-07
    标题 :Process for the synthesis of (2S)-phenyl-3-piperidone
    发明人:LEE JAEMOON; ASKIN DAVID; HOANG THOA
    权利人:MERCK & CO INC
    摘要:The present invention is concerned with novel processes for the preparation of (2S)-phenyl-3-piperidone. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

    专利号:US-2024287010-A1
    优先权日:2021-06-23
    标题:Process For Making Epoxide Derivatives of Farnesene and Use Thereof in Further Synthesis
    发明人:PERSIANI GIACOMO; BAUMGARTNER CORINNE; GRANIER THIERRY; LOVCHIK MARTIN; SCHROEDER FRIDTJOF
    权利人:GIVAUDAN SA
    摘要:Described herein are methods for making intermediates in the production of fragrance ingredients starting from β-farnesene. In particular, methods for making acetylmethylfarnesol and hydroxy-farnesylacetone are described. Methods for making other intermediates in the process are also described. In addition, compositions comprising intermediates in the process and uses of the intermediates are described.

    专利号:US-6310221-B1
    优先权日:1998-07-03
    标题:Methods for synthesis of substituted tetrahydrofuran compound

    专利号:US-6566538-B1
    优先权日:1998-07-03
    标题:Substituted oxygen alicyclic compounds, including methods for synthesis thereof
    发明人:CHORGHADE MUKUND SHANKAR; GURJAR MUKUND KESHAO; KRISHNA PALAKODETY RADHA; LALITHA SISTA VENKATA SAI; SADALAPURE KASHINATH; ADHIKARI SUSANTA SEKHAR; MURUGAIAH ANDAPPAN MURUGAIAH S; RAO BATCHU VENKATESWARA; KRISHNA LEVADALA MURALI; MHASKAR SUNIL VYANKATESH; SHARMA GANGAVARAM VASANTHA MAD; PRASAD TANGALLAPALLY RAJENDRA; SREENIVAS PUNNA; REDDY VAVILALA GOVERDHAN; ISLAM AMINUL; RAO ALLA VENKATA RAMA; LANKA HYMAVATHI; REDDY BETHI SRIDHAR; PRASAD CHITTINENI HARI
    权利人:MILLENNIUM PHARM INC
    摘要:The invention provides new methods for preparation of cyclic oxygen compounds, including 2,5-disubstituted tetrahydrofurans, 2,6-disubstituted tetrahydropyrans, 2,7-disubstituted oxepanes and 2,8-oxocanes. The invention also provides new cyclic oxygen compounds and pharmaceutical compositions and therapeutic methods that comprise such compounds.

    专利号:EP-1102759-A1
    优先权日:1998-07-03
    标题:Methods for synthesis of substituted tetrahydrofuran compound

    专利号:AU-4731199-A
    优先权日:1998-07-03
    标题:Methods for synthesis of substituted tetrahydrofuran compound
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    合成参考文献


    摘要:Merck Index - O'Neil MJ, Heckelman PE, Dobbelaar PH, Roman KJ (eds). The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 15th Ed. Cambridge, UK: The Royal Society of Chemistry, 2013.
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