CAS: 1084-65-7; 6-Methylthiochromane-7-Sulfonamide 1,1-Dioxide

该化合物是一个主要在生物化学和药理学领域引起兴趣的化学化合物,众所周知,它作为某些生物途径的强大抑制剂,特别是细胞扩散和癌症发展过程中的阻遏剂,其作用是明显抑制某些生物途径,特别是细胞扩散和癌症发展;复合物具有有助于其生物活动的具体结构特征,包括有助于与目标蛋白质互动的功能组;已研究逮捕人的潜在治疗用途,特别是在癌症治疗方面,因为逮捕人能够破坏血管产生和肿瘤生长;此外,其溶液和各种溶剂的稳定性使它成为药物配方方面进一步研究的候选物;然而,与许多生物活性化合物一样,其安全性特征和潜在副作用是正在进行的调查的关键领域;

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上下游产品

6-甲基-1,1-二氧代-3,4-二氢-2H-苯并噻喃-7-磺酰氯 3,4-Dihydro-6-Methyl-2H-1-Benzothiopyran-7-Sulphonyl Chloride 1,1-Dioxide 1084-64-6

合成工艺路线路线简述

    📜6-甲基-1,1-二氧代-3,4-二氢-2H-苯并噻喃-7-磺酰氯 以94%的收率获得
    参考文献:Hakamypa,Tatsuya;Nisiyama,Kodzi;Morimoto,Mamoru;Umehno,Masayuki
    标题:Hakamypa,Tatsuya;Nisiyama,Kodzi;Morimoto,Mamoru;Umehno,Masayuki

    专利信息


    专利号:US-10925977-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
    发明人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
    权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
    摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

    专利号:US-11406709-B2
    优先权日:2014-09-15
    标 题 :Therapeutic and research application of PDCL3
    发明人:RAHIMI NADER
    权利人:UNIV BOSTON
    摘要:Described herein are novel compositions comprising, for example, PDCL3 polypeptides having VEGFR-2 inhibitory activity, inhibitory PDCL3 antibodies and PDCL3-binding fragments thereof, or PDCL3 inhibitory nucleic acid molecules, and methods of their use in anti-angiogenesis and anti-tumor proliferation and invasiveness therapies, such as the treatment of cancer, as well as the treatment of those vascular diseases where pathological angiogenesis plays a role, such as in carotid artery disease, macular degeneration, and plaque neovascularization. Also described herein are novel compositions comprising engineered PDCL3 polypeptides having enhanced chaperone activity, recombinant cells comprising such engineered PDCL3 polypeptides having enhanced chaperone activity, and methods thereof for therapeutic protein production and in vitro protein synthesis.

    专利号:US-10814013-B2
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A2
    优先权日:2006-10-05
    标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:AU-2007308022-A1
    优先权日:2006-10-05
    标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

    专利号:US-2008107598-A1
    优先权日:2006-10-05
    标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Boissier JR, Hirtz J, Dumont C, Gérardin A. [Resorption, distribution, excretion and metabolism in rat of a new diuretic: meticrane]. Ann Pharm Fr. 1970 Jul-Aug;28(7):497-509. French. French.
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