CAS: 80-03-5; N-(4-Sulfanilyl-Phenyl)-Glycine
该化合物是一种有机化合物,其特点是其磺酰胺结构,包括附于一个矿泉的磺酰胺组;它是在水中溶解并表现出略微苦味的白色晶状固体,主要以其作为抗生素而闻名,并被用于治疗细菌感染;Acediasulfone功能,通过干扰叶酸合成阻止细菌生长,而叶酸合成是细菌细胞扩散必不可少的;除了其药物用途外,还研究其可能用于各种生物化学研究领域;该化合物在标准条件下一般稳定,但应谨慎处理,因为其潜在副作用和细菌抗药性的发展;同许多磺酰胺一样,必须监测敏感人群的过敏反应;
- 英文名称N-(4-Sulfanilyl-Phenyl)-Glycine
- 中文名称N-[4-[(4-氨基苯基)磺酰基]苯基]甘氨酸
- IUPAC名称N-(4-((4-Aminophenyl)sulphonyl)phenyl)glycine
- 其它别名Glycine,N-(p-sulfanilylphenyl)- (6CI,8CI); Acediasulfone; Ciloprin; N-(p-Sulfanilylphenyl)glycine; N-[p-(p-Aminophenylsulfonyl)phenyl]glycine; p,p'-Diaminodiphenyl sulfone-N-acetic acid
- CAS编号80-03-5
- MFCD编号:MFCD00865990
- EINECS号:201-243-7
- FDA UNII编号:30YP2YHH8W
- 分子式:C14H14N2O4S分子量:306.34
- 产品CID: 2361994
- 产品分类有机原料 → 有机酸及其衍生物 → 羧酸及其衍生物
物理性质
MSDS等安全信息
上下游产品
N-(4-Sulfanilyl-Phenyl)-Glycine Ethyl Ester 101289-55-8N-[4-(4-Nitro-Benzenesulfonyl)-Phenyl]-Glycine Ethyl Ester 17929-46-3
氨苯砜 Dapsone 80-08-0
合成工艺路线路线简述
📜4'-Nitro-4-N-Tosylaminodiphenyl Sulfide置于盐酸,硫酸,双氧水,镍体系中,化学反应生成 N-[4-[(4-氨基苯基)磺酰基]苯基]甘氨酸
参考文献:Khosla Et Al.,Journal Of Scientific And Industrial Research,1955,Vol. 14 C,P. 222,225
标题:Khosla Et Al.,Journal Of Scientific And Industrial Research,1955,Vol. 14 C,P. 222,225
海关参考信息
- 2912110000-甲醛
2912120000-乙醛
2915110000-甲酸
2915211900-乙酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2007021349-A1
优先权日:2005-04-28
标题:Orthogonally protected bifunctional amino acid
发明人：SRINIVASAN ANANTH; LUYT LEONARD G
权利人:SRINIVASAN ANANTH; LUYT LEONARD G
摘要:The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.
专利号:WO-2006114323-A3
优先权日:2005-04-28
标题 :Orthogonally protected bifunctional amino acid
发明人：SRINIVASAN ANANTH; LUYT LEONARD G
权利人:SCHERING AG; SRINIVASAN ANANTH; LUYT LEONARD G
摘要:The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding Compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Mohammad MA, Zawilla NH, El-Anwar FM, Aly SM. Column and thin-layer chromatographic methods for the simultaneous determination of acediasulfone in the presence of cinchocaine, and cefuroxime in the presence of its hydrolytic degradation products. J AOAC Int. 2007 Mar-Apr;90(2):405-13.
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