CAS: 73-63-2; 1-Phenyl-3-(Piperidin-1-yl)Propan-1-One

上下游产品

piperidine formaldehyd 3-oxo-3-phenylpropionic acid 3-bromo-1-phenylpropan-1-one 2-(1-phenyl-3-piperidino-propyl)-pyridine 3-phenyl-1-piperidino-heptan-3-ol 5-methyl-3-phenyl-1-piperidin-1-yl-hexan-3-ol 3-phenyl-1-piperidino-nonan-3-ol

📜3-氯代苯丙酮置于sodium Iodide体系中,用 丙酮,乙腈 作为反应溶剂,化学反应生成 3-(1-哌啶基)苯丙酮盐酸盐
参考文献:Popov,A. F.; Piskunova,Zh. P.; Matvienko,V. N.,Journal Of Organic Chemistry Ussr (English Translation),1986,Vol. 22,# 10,P. 1918-1921
标题:Popov,A. F.; Piskunova,Zh. P.; Matvienko,V. N.,Journal Of Organic Chemistry Ussr (English Translation),1986,Vol. 22,# 10,P. 1918-1921

专利信息

专利号:EP-0558321-A1
优先权日:1992-02-27
标题:Antivirally active N-cycloalkyl alkanol compounds
发明人：KURONO MASAYASU; BABA YUTAKA; OKA MITSURU; HONDA NAOKI; MATSUMOTO YUKIHARU; KAKIGAMI TAKUJI; IWATA NORIYUKI; ISHIWATA YOSHIRO; OHTUKA TAMAKI C O SANWA KAGAKU; MITANI TAKAHIKO; SAWAI KIICHI
权利人:SANWA KAGAKU KENKYUSHO CO
摘要:The compounds are of the general formulan n orn n where Râ‚? is -OH, amino or -SH, Râ‚‚ is H, α- or β-naphthyl or optionally substituted phenyl, R₃ is mono-, di- or tricycloalkyl of C6-16, optionally substituted, R₄₋₇ are H or alkyl, R₈₋₉ are alkyl or may form a 6-membered ring or a 5-membered ring with R₆ and R₇, Râ‚?â‚€ and Râ‚?â‚? are alkyl, and n is 0 or an integer. n Synthesis examples are given, and for the preparation of starting materials. n Pharmaceutical compositions for oral, topical or injectable administration contain the compounds or their acceptable salts. n The compounds have excellent antiviral activity as illustrated against herpes virus and may also be effective against influenza, DNA, RNA and HIV viruses.