CAS: 573762-62-6; 5-Amino-3-(Trifluoromethyl)Picolinonitrile

相似化合物

573762-57-9 1402664-67-8 951753-87-0

上下游产品

CAS号573762-57-9 2-氰基-5-硝基-3-(三氟甲基)吡啶 | CAS号887707-23-5 2-羟基-5-碘-3-(三氟甲基)吡啶 | CAS号887707-25-7 2-氯-5-碘-3-三氟甲基吡啶 | CAS号956104-40-8 阿帕他胺

5-{[(4-Methoxyphenyl)Methyl]Amino}-3-(Trifluoromethyl)Pyridine-2-Carbonitrile 以>95的收率获得产物5-氨基-3-(三氟甲基)氰基吡啶
参考文献: Imidazole Diketone Compound And Use Thereof[fr] Composé Imidazole-Dicétone Et Son Utilisation
标题: Imidazole Diketone Compound And Use Thereof[fr] Composé Imidazole-Dicétone Et Son Utilisation
摘要:提供了一类咪唑二酮类化合物及其制备方法和用途.所述化合物,具有非常好的药代动力学和/或药效学性能,因此可作为雄性激素受体拮抗剂,进而可适用于制备治疗雄性激素相关疾病(如癌症等)的药物.

专利信息

专利号:US-9926291-B2
优先权日:2007-03-27
标 题 :Synthesis of thiohydantoins
发明人：OUERFELLI OUATHEK; DILHAS ANNA; YANG GUANGBIN; ZHAO HONG
权利人:SLOAN KETTERING INST CANCER RES
摘要:A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52.

专利号:WO-2013056547-A1
优先权日:2011-10-22
标题 :Synthesis of a group of hydantoin derivatives and use thereof
发明人：CHEN DEGUI
权利人:CHEN DEGUI
摘要:Provided in the present invention are the pharmaceutical composition, synthesis procedure and medicinal use of a group of HYDANTOIN derivatives. Since these compounds have an inhibiting effect on an androgen receptor, the compounds can be used to treat prostate cancer and other diseases and physiological disorders related to androgen receptor activity.

专利号:WO-2008119015-A2
优先权日:2007-03-27
标 题 :Synthesis of thiohydantoins

专利号:US-8987452-B2
优先权日:2007-03-27
标 题:Synthesis of thiohydantoins

专利号:US-2010190991-A1
优先权日:2007-03-27
标题 :Synthesis of thiohydantoins

专利号:US-9512103-B2
优先权日:2007-03-27
标题:Synthesis of thiohydantoins