CAS: 526-08-9; 4-Amino-N-(1-Phenyl-1H-Pyrazol-5-yl)Benzenesulfonamide

上下游产品

H-pyrazol-3-ylsulfamoyl)-phenyl]-carbamic acid ethyl ester[4-(2-phenyl-2H-pyrazol-3-ylsulfamoyl)-phenyl]-carbamic acid ethyl ester p-acetylaminobenzenesulfonyl chloride 4-AcetylsulfaphenazoleN4-Acetylsulfaphenazole 1-phenylpyrazol-5-amine4-[(1H-Benzoimidazol-2-ylmethyl)-amino]-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide 4-(2-Amino-4-phenyl-thiazol-5-ylazo)-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide 4-[(5-Nitro-1H-benzoimidazol-2-ylmethyl)-amino]-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide 4-[2-Amino-4-(3-amino-phenyl)-thiazol-5-ylazo]-N-(2-phenyl-2H-pyrazol-3-yl)-benzenesulfonamide

📜[4-(2-Phenyl-2H-Pyrazol-3-Ylsulfamoyl)-Phenyl]-Carbamic Acid Ethyl Ester置于sodium Hydroxide体系中,化学反应生成 磺胺苯吡唑
参考文献:New Aminobenzene Sulfonamide
标题:New Aminobenzene Sulfonamide

专利信息

专利号:US-2025179033-A1
优先权日:2021-12-30
标 题 :New antiviral triazole derivatives, their synthesis and their use for treatment of mammalian viral infections
发明人：MAKAROV VADIM; RIABOVA OLGA; LANE THOMAS R; EKINS SEAN
权利人:COLLABORATIONS PHARMACEUTICALS INC; FEDERAL RES CENTER FUNDAMENTALS OF BIOTECHNOLOGY RUSSIAN ACADEMY OF SCIENCE
摘要:A family of triazole derivatives is described. Also described is the use of these triazole derivatives in treating or preventing viral infections, such as human immunodeficiency virus (HIV) infections, and the diseases caused by these infections, such as acquired immunodeficiency syndrome (AIDS). The triazole derivatives, for example, comprise a central triazole group with two substituents comprising an aryl or heteroaryl group. Exemplary derivatives showed excellent HIV inhibitory activity against both wild-type and selected mutant strains of HIV.

专利号:US-10550127-B1
优先权日:2017-02-08
标题:Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes
发明人：ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R, R 1 , R 2 , m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-6103865-A
优先权日:1998-08-03
标 题 :PH-sensitive polymer containing sulfonamide and its synthesis method
发明人：BAE YOU HAN; PARK SANG YEOB
权利人:KWANGJU INST SCI & TECH
摘要:There are disclosed pH-sensitive polymers containing sulfonamide groups, which can be changed in physical properties, such as swellability and solubility, depending on pH and which can be applied for a drug-delivery system, bio-material, sensor, etc, and a preparation method therefor. The pH-sensitive polymers are prepared by introduction of sulfonamide groups, various in pKa, to hydrophilic groups of polymers either through coupling to the hydrophilic groups, such as acrylamide, N,N-dimethylacrylamide, acrylic acid, N-isopropylacrylamide, etc, of polymers or copolymerization with other polymerizable monomers. These pH-sensitive polymers may have a structure of linear polymer, grafted copolymer, hydrogel or interpenetrating network polymer.

专利号:US-2007021349-A1
优先权日:2005-04-28
标题:Orthogonally protected bifunctional amino acid
发明人：SRINIVASAN ANANTH; LUYT LEONARD G
权利人:SRINIVASAN ANANTH; LUYT LEONARD G
摘要:The present invention concerns novel orthogonally protected amino acids, there production and use for the synthesis of binding compounds usable in the diagnosis and treatment of proliferative diseases, in particular tumor diseases.

专利号:WO-2021038419-A1
优先权日:2019-08-23
标题 :Kinase inhibitors and methods of synthesis and treatment
发明人：ZAVORONKOVS ALEKSANDRS; IVANENKOV YAN; POLYKOVSKIY DANIIL; ALIPER ALEKSANDR
权利人:INSILICO MEDICINE IP LTD
摘要:Compounds that function as kinase inhibitors are provided. The kinase inhibitors can have any structure of the formulae provided herein, such as shown for Compounds 1-4. A pharmaceutical composition can include: the compound of one of the embodiments; and a pharmaceutically acceptable carrier having the compound. A method of inhibiting a kinase can include: providing the compound of one of the embodiments described herein to the kinase such that the kinase is inhibited. The methods can include inhibiting DDR1 and/or DDR2, and thereby providing a modulation or decrease in the activity of DDR1 and/or DDR2. This decrease in DDR1 and/or DDR2 activity can be used as therapy to treat conditions related to DDR1 and/or DDR2 activity, such as fibrosis, cancer, and others.

专利号:US-10253004-B2
优先权日:2017-01-26
标 题:Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
发明人：ECKHARDT MATTHIAS; WAGNER HOLGER; PETERS STEFAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of formula I, n nwherein the groups R, R 1 , R 2 , R 3 , m and n are defined herein, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.