CAS: 51023-76-8; 4-Acetamido-4'-Isothiocyanatostilbene-2,2'-Disulfonic Acid, Sodium Salt

该化合物是一种合成有机化合物,其结构复杂,包括一个磺酸组,一个乙基氨基组和一个异硫氰酸藻.该化合物一般在水中溶解,因为全氟辛烷磺酸组的存在增强了其离子特性.该化合物的特性使其在各种应用中有用,包括作为生物化学分析中的染色剂或试剂.该异丙酸盐组的存在表明潜在的再活性,特别是在核分裂生物替代反应中,可在化学合成中加以利用.此外,该化合物可能展示生物活动,从而引起对制药研究的兴趣.其稳定性和再活性可能受到诸如pH和温度等环境因素的影响,而PH和温度是其处理和应用过程中的重要考虑因素.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-5419966-A
    优先权日:1991-06-10
    标 题 :Solid support for synthesis of 3'-tailed oligonucleotides
    发明人:REED MICHAEL W; MEYER JR RICH B; PETRIE CHARLES R; TABONE JOHN C
    权利人:MICROPROBE CORP
    摘要:A solid support for oligonucleotide synthesis has the structure where CPG represents a controlled pore glass matrix, the wavy line represents a carbon chain covalently linking the NH group with the controlled pore glass matrix, X is 2,2'-dimethoxytrityl or H, and R is alkyl, aryl, arylalkyl, heteroalkyl, or heteroaryl. The dimethoxytrityl group is removed from the solid support by treatment with acid, and the oligonucleotide is built, step-by-step in a conventional synthesizer after attachment of the 3' end of the first oligonucleotide unit to the hydroxyl function connected to the R group.

    专利号:WO-9203464-A1
    优先权日:1990-08-28
    标题 :Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule

    专利号:EP-0547142-A1
    优先权日:1990-08-28
    标题 :Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1016/j.bmcl.2023.129261
    摘要:Demeyer A, Fonteneau L, Liennard M, Foyer C, Weigel P, Laurent AD, Lebreton J, Fleury F, Mathé-Allainmat M. Synthesis and biological evaluation of DIDS analogues as efficient inhibitors of RAD51 involved in homologous recombination. Bioorganic & Medicinal Chemistry Letters. 2023 May;87():129261. doi: 10.1016/j.bmcl.2023.129261.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知