CAS: 452-84-6; 3-Amino-4-Fluorotoluene

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CAS号446-11-7 3-硝基-4-氟甲苯 | CAS号452-62-0 3-溴-4-氟甲苯 | CAS号442-10-4 1-(2-fluoro-5-m... | CAS号446-11-7 3-硝基-4-氟甲苯 | CAS号418762-26-2 4-溴-2-氟-5-甲基苯胺 | CAS号82846-18-2 4-氟-3-甲氧基苯甲酸 | CAS号796967-16-3 利尼伐尼 | CAS号63762-78-7 2-氟-5-甲基苯甲醚 | CAS号63762-79-8 2-氟-5-甲基苯酚 | CAS号128495-45-4 4-氟-3-甲氧基苯甲醇 | CAS号128495-46-5 4-氟-3-甲氧基苯甲醛 | CAS号155310-23-9 2-氟-5-甲基二苯胺 | CAS号192702-01-5 3-氯-4-氟溴苄

3-亚硝基甲苯置于sodium Tetrahydroborate,溶剂黄146,N-氟代双苯磺酰胺,Potassium Nitrate,Copper(L) Chloride,Bis(Dibenzylideneacetone)-Palladium(0)体系中,用 乙醇,乙酸乙酯 作为反应溶剂,化学反应 24.0H,反应生成 2-氟-5-甲基苯胺
参考文献:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
标题:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
摘要:报道了有关阴离子配体促进选择性c-h键氟化的详细机理研究.阴离子配体的作用已通过实验证据和dft计算得以阐明.此外,硝酸盐促进了c-f键的还原性消除,使得各种对称和不对称的偶氮苯能够选择性地进行c-h键氟化,从而获得各种邻氟苯胺.
DOI:10.1039/c9Cc07726J

专利信息

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-5998595-A
优先权日:1996-11-05
标题:Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups
发明人：KUSUMOTO SHOICHI; FUKASE KOICHI
权利人:WAKO PURE CHEM IND LTD
摘要:Azidohalogenobenzyl derivatives of the formula (I) ##STR1## wherein A is a halogen atom, B is a halogen atom or a hydrogen atom, and X is a group reactive with a hydroxy group, methods of protecting hydroxy group(s) using said derivatives, and sugar compounds wherein a hydrogen atom of at least one hydroxy group is substituted by an azidohalogenobenzyl group. According to the present invention, there are provided novel derivatives capable of introducing a group into a compound having hydroxy group(s), which group is useful as a stable hydroxy-protecting group even in solid phase synthesis for the purpose of the extension of sugar chain under continuous acidic conditions and of being removed under mild conditions; sugar compounds protected by using said derivatives; and methods of protecting hydroxy group(s) using said derivatives.

专利号:US-6417195-B1
优先权日:1999-02-22
标题 :Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：LEBL MICHAL
权利人:LION BIOSCIENCE AG
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinoline derivatives as well as novel libraries comprised of such compounds.

专利号:US-5874443-A
优先权日:1995-10-19
标 题:Isoquinoline derivatives and isoquinoline combinatorial libraries
发明人：KIELY JOHN S; GRIFFITH MICHAEL C
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides the synthesis of heterocyclic compounds based on the isoquinoline ring. More specifically, the invention provides novel isoquinolines as well as novel libraries comprised of many such compounds, and methods of synthesizing the libraries.

专利号:US-7439382-B2
优先权日:2002-05-17
标题 :4-alkyl-2-haloaniline derivatives and process for producing the same
发明人：NISHIZUKA TOSHIO; KURIHARA HIROSHI
权利人:MEIJI SEIKA KAISHA
摘要:The present invention relates to a compound of formula (1), wherein R 1 , R 2 , R 3 , n, and X are as defined in the specification, and a process for producing the same. This compound is useful as an intermediate for the synthesis of compounds useful as pharmaceuticals or agricultural chemicals.

专利号:EP-2313377-A1
优先权日:2008-08-08
标 题 :Method for stereoselective synthesis of bicyclic heterocyclene