CAS: 3336-43-4; 1-Chloroisoquinolin-4-Ol

相似化合物

1374652-47-7 101774-33-8 3336-60-5

上下游产品

P,P-dichlorophenylphosphine oxide 1,4-dihydroxyisoquinoline 1-chloro-4-methoxyisoquinoline 4-hydroxy-1(2H)-isoquinolinone isoquinoline6-chloro-3,4-dihydro-3-phenyl-2H-1,3-oxazino5,6-cisoquinoline 1-chloro-4-methoxyisoquinoline 1-chloro-4-(phenylmethoxy)isoquinoline 1-chloro-4-({10-[(4'-°Ctyl-1,1'-biphenyl-4-yl)oxy]decyl}oxy)isoquinoline

1-氯-4-甲氧基异喹啉 以 三溴化硼 用作溶剂,以to Give The Corresponding 1-Chloro-4-Hydroxy Isoquinoline (Example 226C)的收率获得1-氯-4-羟基异喹啉
参考文献:Hepatitis C Virus Inhibitors
标题:Hepatitis C Virus Inhibitors
摘要:本发明揭示了一种具有一般式的丙型肝炎病毒抑制剂:其中r1,R2,R3,R',B,Y和x如描述中所述.还揭示了包含该化合物的组合物以及使用该化合物抑制hcv的方法.

专利信息

专利号:US-9067934-B2
优先权日:2011-03-31
标题 :Bicyclic pyridinones
发明人：PETTERSSON MARTIN YOUNGJIN; JOHNSON DOUGLAS SCOTT; SUBRAMANYAM CHAKRAPANI; O'DONNELL CHRISTOPHER JOHN; AM ENDE CHRISTOPHER WILLIAM; FISH BENJAMIN ADAM; GREEN MICHAEL ERIC; MULLINS PATRICK BRADLEY; STIFF CORY MICHAEL; TRAN TUAN PHONG; NAVARATNAM THAYALAN
权利人:PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I n nas defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.