CAS: 2252-63-3; 1-(4-Fluorophenyl)Piperazine

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CAS号821-48-7 二(2-氯乙基)胺盐酸盐 | CAS号371-40-4 4-氟苯胺 | CAS号460-00-4 对氟溴苯 | CAS号110-85-0 哌嗪 | CAS号6163-58-2 三(2-甲苯基)膦 | CAS号4004-97-1 1-(4-fluorophen... | CAS号57260-71-6 1-B°C-哌嗪 | CAS号77697-11-1 双(2-溴乙基)氨基甲酸乙酯 | CAS号105173-87-3 3-[4-(4-fluorop... | CAS号27144-84-9 2-[4-(4-氟苯基)哌嗪-... | CAS号127625-29-0 法南色林 | CAS号330601-48-4 2-CHLORO-1-[4-(... | CAS号76691-03-7 2-Buten-1-one, ... | CAS号76691-08-2 (Z)-1-(3-fluoro... | CAS号76691-19-5 1-(4-fluorophen... | CAS号82211-65-2 2-BENZOXAZOLINO... | CAS号83823-55-6 1-(3,4-Dihydro-... | CAS号90096-18-7 2-[4-(4-fluorop...

4-(4-氟苯基)哌嗪-1-羧酸叔丁酯置于三氟乙酸体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,以83%的收率获得1-(4-氟苯基)哌嗪
参考文献:7-벤질-4(4-페닐피페라진-1-일)-7H-피롤로[2,3-D]피리미딘 유도체 및 이를 유효성분으로 함유하는 피부 미백용 조성물 및 멜라닌 색소 과다 침착 질환의 예방 또는 치료용 약학적 조성물
标题:7-벤질-4(4-페닐피페라진-1-일)-7H-피롤로[2,3-D]피리미딘 유도체 및 이를 유효성분으로 함유하는 피부 미백용 조성물 및 멜라닌 색소 과다 침착 질환의 예방 또는 치료용 약학적 조성물
摘要:这是关于含有7-苄基-4-(4-苯基哌啶-1-基)-7H-吡罗[2,3-D]嘧啶衍生物及其作为有效成分的皮肤美白配方的内容.由于该衍生物即使使用少量也能抑制黑色素的生成,因此可用作预防或治疗黑色素色素过多沉积疾病的药学配方,皮肤美白化妆品配方以及皮肤美白保健食品.

专利信息

专利号:US-8865935-B2
优先权日:2011-06-30
标题:Purification methods for betulonic acid and Boc-lysinated betulonic acid, and organic synthesis of betulonic acid amides with piperazine derivatives
发明人：CHUE KUCK-TACK; KIM TAE-HWAN; TEN LEONID
权利人:CHUE KUCK-TACK; KIM TAE-HWAN; TEN LEONID; KOREA ENERGY RESEARCH INST
摘要:The present invention provides a method of purifying betulonic acid contained the reaction product of organic synthesis of a Jones oxidation reagent and betulin extracted from the bark of a birch, a method of preparing a piperazine betulonic acid amide derivative, which is used as a chemical having an antibacterial function, using the high-purity betulonic acid obtained by the purification method and a derivative prepared by this method, a method of purifying a Boc-lysinated betulonic acid monomer ester contained in the reaction product of organic synthesis of lysine and the high-purity betulonic acid (starting material) obtained by the purification method, and a method of purifying Boc-lysinated betulonic acid contained in the reaction product of hydrolysis of the high-purity Boc-lysinated betulonic acid monomer ester.

专利号:US-2005019747-A1
优先权日:2002-08-07
标 题 :Nanoliter-scale synthesis of arrayed biomaterials and screening thereof
发明人：ANDERSON DANIEL G; LEVENBERG SHULAMIT; LANGER ROBERT S
摘要:A method of screening cell-polymer interactions. The method includes depositing monomers as a plurality of discrete elements on a substrate, causing the deposited monomers to polymerize, thereby creating an array of discrete polymer elements on the substrate, incubating the substrate in a cell-containing culture medium, and characterizing a predetermined cell behavior on each polymer element.

专利号:WO-9919297-A9
优先权日:1997-10-15
标题 :Synthesis of azetidine derivatives
发明人：CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI-MIN
权利人:COELACANTH CHEMICAL CORP; CHEN ZHENGMING; KOLB HARTMUTH C; RICHARDSON PAUL; HUANG ZHI MIN
摘要:The present invention provides compound having formula (I) useful as building blocks for combinatorial libraries and methods of making such compounds. Also provided are compositions comprising the compounds.

专利号:US-6313297-B1
优先权日:1998-01-17
标题:Base-catalyzed synthesis of 1-aryl-4-(aryl ethyl)piperazines from aromatic olefins and 1-arylpiperazines
发明人：HERWIG JUERGEN; BELLER MATTHIAS; BREINDL CLAUDIA
权利人:AVENTIS RES & TECHNOLOGIES; GMBH & CO KG
摘要:A process for preparing a 1-aryl-4-(arylethyl)piperazine of the formula (I)by reacting a 1-arylpiperazine of the formula (II)with an aromatic olefin of the formula (III)in an inert solvent in the presence of at least one basic catalyst, where in the formulae (I) to (III)Ar and Ar' independently of one another are an aryl radical, selected from the group of the fused and unfused C6-C22-aromatics and the fused or unfused C5-C22-heteroaromatics which have at least one nitrogen, oxygen or sulfur atom in the ring; andR1 and R2 independently of one another are a hydrogen atom, a C1-C8-alkyl radical or an aryl radical Ar.

专利号:WO-0063168-A1
优先权日:1999-04-16
标题 :Synthesis of azetidine derivatives
发明人：CHEN ZHENGMING; KOLB HATMUTH C; RICHARDSON PAUL; HUANG ZHI-MIN
权利人:COELACANTH CHEMICAL CORP; CHEN ZHENGMING; KOLB HATMUTH C; RICHARDSON PAUL; HUANG ZHI MIN
摘要:The present invention provides compound having formula (I), useful as building blocks for combinatorial libraries and methods of making such compounds. Also provided is a novel process for synthesizing such compounds. In addition, the present invention includes products made by these processes.

专利号:US-9550000-B2
优先权日:2011-09-09
标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
发明人：ROBINSON SIMON P; YU MING
权利人:ROBINSON SIMON P; YU MING; LANTHEUS MEDICAL IMAGING INC
摘要:The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.