CAS: 22353-38-4; 3-Chloro-2-Hydroxy-5-Nitropyridine

相似化合物

21427-61-2 850663-54-6 198268-98-3

上下游产品

CAS号5418-51-9 2-羟基-5-硝基吡啶 | CAS号22353-40-8 5-硝基-2,3-二氯吡啶 | CAS号22353-35-1 2-氨基-3-氯-5-硝基吡啶 | CAS号4214-76-0 2-氨基-5-硝基吡啶 | CAS号22353-41-9 2-溴-3-氯-5-硝基吡啶 | CAS号22353-40-8 5-硝基-2,3-二氯吡啶 | CAS号130284-52-5 5-氨基-2-溴-3-氯吡啶 | CAS号98121-41-6 5, 6-二氯-3-氨基吡啶 | CAS号110860-92-9 2,3-二氯-5-羟基吡啶 | CAS号130284-56-9 2-溴-3-氯-5-羟基吡啶

📜2-羟基-5-硝基吡啶置于盐酸,Potassium Chlorate体系中,化学反应 0.25H,以93%的收率获得5-硝基-2-羟基-3-氯吡啶
参考文献:Chemistry Of 3-Hydroxypyridine Part 2: Synthesis Of 5,6-Dihalo-3-Hydroxypyridines
标题:Chemistry Of 3-Hydroxypyridine Part 2: Synthesis Of 5,6-Dihalo-3-Hydroxypyridines
摘要:本文介绍了从市售的 2-Hydroxy-5-Nitropyridine 开始,多步骤合成迄今未知的 5,6-二卤-3-羟基吡啶的方法.此外,还探讨了廉价的 2-氨基甲基呋喃(糠胺)在新颖的两步法中制备标题化合物的适用性.
Doi:10.1055/s-1990-26919

专利信息

专利号:US-5144038-A
优先权日:1990-07-17
标题:Process for the production of 2-hydroxy-3-halo-5-nitropyridines
发明人：WORSCH DETLEV
权利人:LONZA AG
摘要:A process for the production of 2-hydroxy-3-halo-5-nitropyridines, in which a 5-halo-6-hydroxynicotinic acid is nitrated in the end product. The resultant pyridines form valuable intermediate products for active ingredient synthesis.

专利号:US-9815842-B2
优先权日:2014-05-28
标题 :Pyrazolo pyrimidine derivatives and their use as MALT1 inhibitors
发明人：SOLDERMANN CAROLE PISSOT; QUANCARD JEAN; SCHLAPBACH ACHIM; SIMIC OLIVER; TINTELNOT-BLOMLEY MARINA; ZOLLER THOMAS
权利人:SOLDERMANN CAROLE PISSOT; QUANCARD JEAN; SCHLAPBACH ACHIM; SIMIC OLIVER; TINTELNOT-BLOMLEY MARINA; ZOLLER THOMAS; NOVARTIS AG
摘要:The present invention describes new pyrazolo-pyrimidine derivatives which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.