CAS: 2096989-55-6; (1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)Cyclopropyl)Amino)-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-3-yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol

该化合物是Ticagrelor的立体异构体,Ticagrelor是著名的P2Y12受体对立物,用作抗塑剂.与Ticagrelor不同的是,ent-Ticagrelor因其对应结构而展示了独特的药理特性,使其对心血管治疗研究很有价值.它独特的结合性及代谢性剖面图提供了结构-活动关系的洞察力,帮助开发了最佳P2Y12抑制剂.Ent-Ticagrelor在临床前研究中特别有用,有助于阐明Ticagrelor及其代谢物的立体特效.该化合物是分析和药理研究的关键参考标准,确保抗塑胶药物研究中对对抗血清和生物活动的精确定性.

英文名称(1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)Cyclopropyl)Amino)-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-3-yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol
中文名称替格瑞洛杂质J
IUPAC名称(1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
其它别名(1R,2R,3S,5R)-3-(7-((1S,2R)-2-(3,4-Difluorophenyl)Cyclopropylamino)-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-3-Yl)-5-(2-Hydroxyethoxy)Cyclopentane-1,2-Diol; Ticagrelor-10; Ticagrelor Impurity 4/ticagrelor Enantiomer Impurity/(1R,2R,3S,5R)-3-[7-[[(1S,2R)-2-(3,4-Difluorophenyl)Cyclopropyl]Amino]-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]-5-(2-Hydroxyethoxy)-1,2-Cyclopentanediol; Ticagrelor Enantiomer Impurity; Ticagrelor Impurity I: Ticagrelor Enantiomer Impurity; 1,2-Cyclopentanediol, 3-[7-[[(1S,2R)-2-(3,4-Difluorophenyl)Cyclopropyl]Amino]-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]-5-(2-Hydroxyethoxy)-, (1R,2R,3S,5R)-; (1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)Cyclopropyl) Amino)-5-(Propylthio)-3H-[1,2,3]Triazolo[4,5-D]Pyrimidin-3-Yl)-5- (2-Hydroxyethoxy)Cyc; Ticagrelor Enatiomer Impurity
CAS编号2096989-55-6
MFCD编号:MFCD25977315
FDA UNII编号:FM6E9CTY52
分子式:C23H28F2N6O4S分子量:522.58
产品CID: 1075744
产品分类有机原料 → 有机杂环化合物 → 三唑并嘧啶类

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