CAS: 177735-11-4; 4-Methyl-3-Thiopheneboronic Acid
该化合物是一种多用途的博尔尼酸衍生物,广泛用作铃木-米亚乌拉交叉相交反应的关键中间体,其硫苯基脊柱和博罗尼酸功能组可有效形成碳-碳债券,使其在制药和材料科学应用中具有价值.4级的甲基替代可增强稳定性和影响反应性,允许有选择地与丙烯或乙烯卤化物结合.该化合物在合成七环化合物和共生系统方面特别有用,通常作为白色供应给高纯度的非白晶状固体,确保合成工作流程的一贯性能.建议在惰性条件下妥善储存以稳定性为目的.
物理性质
MSDS等安全信息
上下游产品
CAS号476620-20-9 4-甲基噻吩-3-硼酸频哪酯合成工艺路线路线简述
📜4-甲基噻吩-3-硼酸频哪酯置于sodium Periodate,水体系中,用 丙酮 用作溶剂,以35%的收率获得4-甲基-3-噻吩硼酸
参考文献:Wo2006/102194
标题:Wo2006/102194
专利信息
专利号:US-7737166-B2
优先权日:2005-08-17
标 题:Antifungal bicyclic hetero ring compounds
发明人：KAWAKAMI KATSUHIRO; KANAI KAZUO; HORIUCHI TAKAO; TAKESHITA HIROSHI; KOBAYASHI SYOZO; SUGIMOTO YUICHI; ACHIWA ISSEI; KUROYANAGI JUNICHI
权利人:DAIICHI SANKYO CO LTD
摘要:A 1,6-β-glucan synthetase inhibitor is provided, having potent growth inhibition and having excellent safety. A compound is provided, capable of expressing in a wide spectral range and specifically or selectively, an antifungal effect based on its functional mechanism of 1,6-β-glucan synthesis inhibition. Also provided is a drug, a salt or hydrate thereof, especially an antifungal that contains the compound. Concretely, provided is a compound of the following formula (I), its salt or hydrate, and a drug or antifungal containing, as the active ingredient, the compound, its salt or hydrate:
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:An Approach To Heterodiarylmethanes Via Sp2-Sp3 Suzuki−miyaura Cross-Coupling作者:Gavin W. Stewart,Peter E. Maligres,Carl A. Baxter,Ellyn M. Junker,Shane W. Krska,Jeremy P. Scott |发布日期:2016.6
摘要:The Synthesis Of A Range Of Structurally Diverse Diarylmethanes Via The Suzuki−miyaura Cross-Coupling Of Aryl Methane Acetates And Arylboronic Acids Is Reported, Including Several Challenging Examples Containing Nitrogen, Oxygen And Sulfur Heteroatoms In One Or Both Coupling Partners. A Single Set Of Optimized Conditions Was Used To Generate The Diarylmethanes In 52-91% Yield.
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