2,6-二羟基苯甲酸置于氯化亚砜,Potassium Carbonate体系中,用 二氯甲烷,N,N-二甲基甲酰胺 用作溶剂,化学反应 24.0H,反应生成嘧啶肟草醚 参考文献:Biological Activity Of The New Herbicide Lgc-40863 {benzophenoneo-[2,6-Bis[(4,6-Dimethoxy-2-Pyrimidinyl)Oxy]Benzoyl]Oxime} 标题:Biological Activity Of The New Herbicide Lgc-40863 {benzophenoneo-[2,6-Bis[(4,6-Dimethoxy-2-Pyrimidinyl)Oxy]Benzoyl]Oxime} 摘要: Doi:10.1002/(Sici)1096-9063(199710)51:2<109::Aid-Ps585>3.0.Co;2-7
专利号:WO-2024256370-A1 优先权日:2023-06-13 标 题 :Synthesis of glufosinate using an amidase-based process 发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.
专利号:US-2025120400-A1 优先权日:2021-12-10 标题:Synthesis of glufosinate using a hydantoinase-based process 发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN 权利人:BASF SE 摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.
专利号:WO-2021130756-A1 优先权日:2019-12-25 标题:Combinations of non-protein amino acids and acetolactate synthase enzyme inhibitors 发明人:KLIPCAN LIRON; VAN-OSS PINHASI RUTH 权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO 摘要:The present invention provides compositions and methods for disrupting protein synthesis in plant cells.
专利号:US-11919928-B2 优先权日:2016-03-16 标题 :Method for producing dihydrotentoxin 发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI 权利人:KUMIAI CHEMICAL INDUSTRY CO 摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.
专利号:US-2021386068-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.
专利号:US-2021352899-A1 优先权日:2018-11-07 标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides 发明人:KISTER JEREMY; SATCHIVI NORBERT M 权利人:CORTEVA AGRISCIENCE LLC 摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.
1: Chang HR, Keum YS, Koo SJ, Moon JK, Kim K, Kim JH. Metabolism of a new herbicide, [(14)c]pyribenzoxim, in rice. J Agric Food Chem. 2011 Mar 9;59(5):1918-23. doi: 10.1021/jf1039469. Epub 2011 Feb 10. Epub 2007 Jun 26. doi: 10.1016/j.pestbp.2016.08.006. Epub 2016 Aug 20.
合成参考文献
参考文献:10.1016/j.pestbp.2016.08.006 摘要:Deng W, Yang Q, Zhang Y, Jiao H, Mei Y, Li X, Zheng M. Cross-resistance patterns to acetolactate synthase (ALS)-inhibiting herbicides of flixweed ( Descurainia sophia L.) conferred by different combinations of ALS isozymes with a Pro-197-Thr mutation or a novel Trp-574-Leu mutation. Pesticide Biochemistry and Physiology. 2017 Mar;136():41–5. doi: 10.1016/j.pestbp.2016.08.006.