CAS: 156-54-7; Sodium Butyrate

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专利信息

专利号:US-2024358747-A1
优先权日:2021-09-01
标 题:SOME GEL FORMULATIONS THAT PROVIDE WOUND HEALING AND THE SYNTHESIS OF DYSPROSIUM ERBIUM BORATE TRIHYDRATE (Dy0.5Er0.5BO3.3H2O) COMPOUND USED IN THESE FORMULATIONS
发明人：UYSAL AYSE ECEM
权利人:VERTRATECH KIMYA SANAYI VE TICARET LTD SIRKETI
摘要:Disclosed is a gel formulation, in which boric acid, metal borate and hyaluronic acid derivatives are used together as an active ingredient, which is rapidly absorbed from the skin, effectively accelerating the skin's self-renewal, removal of redness and scar-free wound healing processes. Additionally disclosed is the synthesis of a novel amorphous, nanostructured bimetallic compound of dysprosium erbium borate trihydrate used in this formulation.

专利号:US-12391691-B2
优先权日:2018-11-16
标题:Synthesis of key intermediate of KRAS G12C inhibitor compound
发明人：PARSONS ANDREW THOMAS; COCHRAN BRIAN MCNEIL; POWAZINIK IV WILLIAM; CAPORINI MARC ANTHONY
权利人:AMGEN INC
摘要:The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure n nuseful for the synthesis of compounds that target KRAS G12C mutations, such as

专利号:US-2025206736-A1
优先权日:2019-11-14
标题 :Synthesis of kras g12c inhibitor compound
发明人：CORBETT MICHAEL THOMAS; CAILLE SEBASTIEN
权利人:AMGEN INC
摘要:The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.

专利号:US-7001625-B2
优先权日:2001-07-30
标 题:Solid phase synthesis of salts of organic acids including butyric acid
发明人：VAN DYCK STEFAAN; ADAMS CLIFFORD; MEEUSEN ANDRE; VAN CAMPENHOUT LEEN
权利人:KEMIN IND INC
摘要:A process for the solid-phase synthesis of salts of organic acids in a granular, free-flowing, and dust-free form particularly suited for use as animal feed additives. A mixture of liquid organic acids, including butyric acid, is applied to an inert, absorbent carrier. A solid base is then added during stirring. The acid is slowly released from the carrier preventing the fast reactions that lead to the formation of clumps. The exothermic reaction releases heat which assists in reducing the moisture content of the product. The addition of butyric acid results in a product which has an improved effect on animal growth over the animal feed additive without the addition of butyric acid.

专利号:US-2025206743-A1
优先权日:2022-03-25
标 题:Tyk2 inhibitor synthesis and intermediates thereof
发明人：MASSE CRAIG E; PHADKE AVINASH S; LAWSON JON P; LEVY STUART; YANG XIAOWEI; WU GUISHENG; FAN SHUFENG
权利人:TAKEDA PHARMACEUTICALS CO
摘要:Described herein are methods of synthesis of a tyrosine-protein kinase 2 (TYK2) inhibitor and to intermediate compounds of the synthesis and methods of making the intermediates. Also provided are pharmaceutically acceptable compositions including compounds prepared by the synthetic method and methods of treating disorders using the same.

专利号:US-8536318-B2
优先权日:2008-05-29
标题 :Chemical RNA synthesis method
发明人：DEBART FRANCOISE; VASSEUR JEAN-JACQUES; LAVERGNE THOMAS
权利人:DEBART FRANCOISE; VASSEUR JEAN-JACQUES; LAVERGNE THOMAS; CENTRE NAT RECH SCIENT; UNIV MONTPELLIER 2
摘要:The invention relates to a method for the chemical synthesis of RNA, comprising the following steps: a) bonding to a solid support of a monomer having formula (II) in which—X 1 is a dimethoxytrityl group,—X 6 is H or an OAc group or OX 3 , in which X 3 is a group having formula (A), in which X is O or S, R′ is H or CH 3 and R is selected from a linear or branched alkyl group at C 1 to C 4 and a R 1 —O—R 2 group in which R 1 is an alkyl group at C 1 to C 2 and R 2 is a CH 3 group or CH 2 CH 2 —O—CH 3 or aryl; b) assembly with the monomer having formula (II) bound to the support thereof obtained in step (a) of at least one monomer having formula (III) in which X 1 , Bp, X 3 are as defined for formula (II) and X 5 is a hydrogen phosphonate monoester or phosphoramidite group, preferably a 2-cyanoethyl-N,N-diisopropylphosphoramidite group, which is used to obtain a protected single-strand RNA bound to a support.