CAS: 13031-60-2; H-?-Abu-Ome.Hcl

该化合物是一种有机化合物,其特点是有矿和酯功能组,是伽马-氨基丁酸(GABA)的衍生物,经常用于生化研究和药物应用,通常以白到白的晶状粉形式出现,在水中溶解,便于其用于各种水成品,其分子结构包括一个甲基酯组,有助于其反应和潜在的生物活动.甲基四氨基甲基丁基氢氯化氢因其作为...

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85909-04-2 13325-10-5 56-12-2

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CAS号85909-04-2 4-(B°C-氨基)丁酸甲酯 | CAS号67-56-1 甲醇 | CAS号56-12-2 4-氨基丁酸 | CAS号13013-02-0 甲基-4-硝基丁酸 | CAS号5959-35-3 4-aminobutyric ... | CAS号5291-77-0 N-苄基吡咯烷酮 | CAS号554-68-7 三乙胺盐酸盐 | CAS号67706-63-2 methyl 4-(pheny... | CAS号600142-99-2 methyl 4-(2-oxo... | CAS号61454-85-1 4-[1-(4-phenylp... | CAS号62210-26-8 4-异硫代氰酰基丁酸甲酯 | CAS号51642-06-9 4-IS°CYANOBUTYR...

合成工艺路线路线简述

    📜4-氨基丁酸 反应生成4-氨基丁酸甲酯盐酸盐
    参考文献:Methotrexate Derivative
    标题:Methotrexate Derivative
    摘要:揭示的化合物由以下式表示:##str1## 其中 R.Sup.1:Ch.Sub.2,Ch.Sub.2 Ch.Sub.2,Ch.Sub.2 O,Ch.Sub.2 S,Ch.Sub.2 So;R.Sup.2:氢原子,具有1至4个碳原子的较低烷基基团或苄基团;N:1至4的整数;R.Sup.3:Coor.Sup.4,Nhcor.Sup.5,Conr.Sup.6 R.Sup.7,Po.Sub.3 H.Sub.2,So.Sub.3 H.该化合物表现出强效的抗风湿功能,治疗银屑病功能和抗癌功能,并具有低毒性,因此可用作药物.

    海关参考信息

    专利信息


    专利号:US-8338621-B2
    优先权日:2005-12-21
    标题:Process for the preparation of 2-oxo-1-pyrrolidine derivatives
    发明人:SURTEES JOHN; BOUVY DIDIER; THOMAS ANTOINE; COMBRET YVES; FRANK MICHAEL; SCHMIDT GUNTHER; DUCHENE GUY
    权利人:SURTEES JOHN; BOUVY DIDIER; THOMAS ANTOINE; COMBRET YVES; FRANK MICHAEL; SCHMIDT GUNTHER; DUCHENE GUY; UCB SA
    摘要:The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) n n n n n n n n n n Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.

    专利号:US-6797479-B2
    优先权日:1995-04-04
    标题 :Reagents and methods for the detection and quantification of vancomycin in biological fluids
    发明人:ADAMCZYK MACIEJ; BRATE ELAINE M; PERKOWITZ MARY M; REGE SUSHIL D
    权利人:ABBOTT LAB
    摘要:Immunoassay reagents, methods and test kits for the specific quantification of vancomycin in a test sample are disclosed. The reagent comprises antibodies prepared with immunogens of FIG. 6 wherein P is an immunogenic carrier material and X is a linking moiety. Also described is the synthesis of labeled reagents of FIG. 8 wherein Q is a detectable moiety, preferably fluorescein or a fluorescein derivative, and X is a linking moiety.

    专利号:WO-9213530-A1
    优先权日:1991-02-11
    标题 :Transglutaminase enzyme inhibitors
    发明人:CHEN GEORGE T
    权利人:MEDICIS CORP
    摘要:The present invention relates to a composition and method for regulating protein crosslinking by transglutaminase enzymes in an animal or human. More particularly, the present invention relates to a series of novel transglutaminase enzyme inhibitors having the general formula: R-C=O-(CH2)n-NCS, wherein R is selected from the group consisting of O-CH3, O-CH2-CH3, O-Ø, O-Bz, and NH2 and n is an integer between 1 and 4, to their synthesis, and to their use in the treatment of crosslinking and amine incorporation disorders.

    专利号:CN-105399711-A
    优先权日:2015-11-13
    标 题 :A kind of synthesis method of carbofuran carboxylated hapten

    专利号:CN-105399711-B
    优先权日:2015-11-13
    标题 :A kind of synthesis method of carbofuran carboxylated hapten

    专利号:US-6472403-B2
    优先权日:2000-01-20
    标 题 :αV integrin receptor antagonists
    发明人:DUGGAN MARK E; HALCZENKO WASYL; HUTCHINSON JOHN H; LI AIWEN; MEISSNER ROBERT S; PERKINS JAMES J; STEELE THOMAS G; WANG JIABING; PATANE MICHAEL A
    权利人:MERCK & CO INC
    摘要:The present invention relates to novel imidazolidinone derivatives thereof, their synthesis, and their use as αv integrin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the integrin receptors αvβ3 and/or αvβ5 and are useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting vascular restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, inflammatory arthritis, viral disease, cancer, and metastatic tumor growth.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: I N Tiurenkov, Et Al. [参考文献]: Farmakol Toksikol. 1986 Nov-Dec;49(6):31-4.
    [参考文献]: Michael R Emmett, Et Al. Tandem Ring-Opening Decarboxylation Of Cyclopropane Hemimalonates With Sodium Azide: A Short Route To γ-Aminobutyric Acid Esters. J Org Chem. 2012 Aug 3;77(15):6634-7.

    合成参考文献


    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 478.
    摘要:Biochemical Pharmacology., 32(1093), 1983 []
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