CAS: 62476-56-6; 3-Amino-2,6-Dichloropyridine

相似化合物

16013-85-7 6298-19-7 5350-93-6

上下游产品

CAS号16013-85-7 2,6-二氯-3-硝基吡啶 | CAS号462-08-8 3-氨基吡啶 | CAS号762-04-9 亚磷酸二乙酯 | CAS号32263-14-2 4-羟基-3-甲氧基-5-甲基苯甲醛 | CAS号3430-33-9 3-氨基-2,6-二甲基吡啶 | CAS号7647-01-0 盐酸 | CAS号7732-18-5 水 | CAS号7722-84-1 过氧化氢 | CAS号5350-93-6 2-氯-5-氨基吡啶 | CAS号109202-21-3 5-氯-2-甲基噻唑并[5,4-b]吡啶 | CAS号31784-71-1 5-氯噻唑并[5,4-b]吡啶-2-胺 | CAS号142670-86-8 3-(N-Methylamin... | CAS号189393-12-2 N-(2,6-dichloro... | CAS号240815-51-4 N-(2,6-二氯吡啶-3-基... | CAS号240815-52-5 2-氯咪唑并[1,5-a]吡啶... | CAS号52208-50-1 2,6-二氯-3-氟吡啶 | CAS号140413-07-6 2-chloro-5-meth... | CAS号133627-12-0 2-chloro-11-eth... | CAS号121879-69-4 5-氯噻唑并[5,4-b]吡啶...

烟酰胺置于盐酸,Aluminum (Iii) Chloride,Sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应生成 2,6-二氯-3-氨基吡啶
参考文献:烟酰胺合成2,3,6-三氯吡啶的工艺研究
标题:烟酰胺合成2,3,6-三氯吡啶的工艺研究
摘要:本发明提供了一种烟酰胺合成2,3,6‑三氯吡啶的工艺研究,以烟酰胺为原料,碱性环境下加入次氯酸钠溶液,进行霍夫曼降级反应,得到3‑氨基吡啶,其在路易斯酸催化剂催化下,与浓盐酸/双氧水条件下进行氯化反应制得2,6‑二氯‑3‑氨基吡啶,再在低温,强酸条件下,经亚硝酸钠作用反应生成重氮盐溶液,最后经桑德迈尔反应反应生成目标产物-2,3,6‑三氯吡啶,本发明提供的工艺原料简单,易得并且价格便宜,反应条件简单容易操作,后处理简单,收率高,具有非常好的工业开发前景.

专利信息

专利号:US-4897484-A
优先权日:1986-12-19
标题 :Process for the preparation of substituted pyridines
发明人：WEIS CLAUS D; SUTTER PETER
权利人:CIBA GEIGY CORP
摘要:A process is described for the preparation of compounds of the formula (1) in which R and X are as defined in claim 1. The compounds of the formula (1) are valuable intermediates in the synthesis of triarylmethane dyes and triarylmethanelactones.

专利号:WO-2025077857-A1
优先权日:2023-10-13
标题:Use of prmt5 inhibitor in treatment of tumors or cancers
发明人：YAO BING; GU XIAOHUI; MAO WEIFENG; ASWAD FRED JULLIEN; JOSEPH JAMES DAVID; LI MINGXI
权利人:SHANGHAI APEIRON THERAPEUTICS COMPANY LTD
摘要:The present disclosure describes a novel molecule having protein arginine methyltransferase 5 inhibitory activity, and methods for synthesis and use of a compound. Specifically, the present disclosure describes a compound of formula (I) or a pharmaceutically acceptable salt, hydrate or solvate thereof, and methods for synthesis and use of the compound.

专利号:WO-2009018502-A2
优先权日:2007-08-01
标 题:Process for the synthesis of diaminopyridine and related compounds

专利号:CN-119751277-A
优先权日:2024-12-31
标 题:Synthesis of high-purity 2,2'-[[(1S,2S)-1,2-(-)-1,2-(-)]-bis[6-(1,1- (-)]phenol

专利号:JP-2010535249-A
优先权日:2007-08-01
标 题 :Method for the synthesis of diaminopyridine and related compounds

专利号:EP-2176224-A2
优先权日:2007-08-01
标题 :Process for the synthesis of diaminopyridine and related compounds