CAS: 584-03-2; Butane-1,2-Diol

相似化合物

40348-66-1 73522-17-5 5077-67-8

上下游产品

CAS号497-06-3 丁烯二醇 | CAS号56-81-5 甘油 | CAS号5077-67-8 1-羟基-2-丁酮 | CAS号62214-39-5 (S)-3-丁烯-1,2-二醇 | CAS号106-88-7 1,2-环氧丁烷 | CAS号9004-34-6 微晶纤维素 | CAS号50-70-4 山梨醇 | CAS号110-63-4 1,4-丁二醇(BDO) | CAS号124-38-9 二氧化碳 | CAS号201230-82-2 carbon monoxide | CAS号3347-90-8 S-2-羟基丁酸 | CAS号3131-63-3 2-乙基苯并呋喃 | CAS号147794-11-4 2-hydroxybutyl ... | CAS号147794-12-5 1-hydroxybutan-... | CAS号143693-24-7 (R)-2-羟基丁基甲苯磺酸 | CAS号14869-00-2 1-(Benzyloxy)-2... | CAS号101515-10-0 2-benzyloxybutanol | CAS号4437-85-8 4-乙基-1,3-二恶烷-2-酮 | CAS号5077-67-8 1-羟基-2-丁酮 | CAS号4417-81-6 2-氧代丁醛

(R)-1-(Benzyloxy)Butan-2-Ol置于palladium 10% On Activated Carbon,氢气体系中,用 乙醇 作为反应溶剂,以79%的收率获得产物1,2-丁二醇
参考文献:酶介导的带有不饱和取代基的1,2-二醇单甲苯磺酸酯衍生物的对映体选择性水解
标题:酶介导的带有不饱和取代基的1,2-二醇单甲苯磺酸酯衍生物的对映体选择性水解
摘要:我们已经成功地通过酶水解容易地制备了带有不饱和取代基的光学活性的1,2-二醇单甲苯磺酸酯.脂肪酶ps快速催化具有双键的2-乙酰氧基丁-3-烯基甲苯磺酸酯和具有三键的2-乙酰氧基丁-3-炔基甲苯磺酸酯的水解,具有出色的对映选择性,可提供相应的旋光化合物.该反应也适用于在末端具有双键的较长链的乙酸酯.为了证明该方法的适用性,已从外消旋的2-乙酰氧基戊-4-烯基甲苯磺酸酯中分几步合成了对映体纯的(R)-马苏阿内酯,一种天然椰子香精.此外,该酶可以识别烯烃的立体化学,而(z)-烯基结构比(e)-异构体更适合于对映选择性水解.
DOI:10.1016/j.Tet.2018.05.087

专利信息

专利号:US-2010099894-A1
优先权日:2006-10-09
标 题 :Method for the Synthesis of Cyclic Acetals by the Reactive Extraction of a Polyol in a Concentrated Solution
发明人：DUBOIS JEAN-LUC; IBORRA CHORNET SARA; VELTY ALEXANDRA I LUCIENNE; CORMA CANOS AVELINO
权利人:DUBOIS JEAN-LUC; IBORRA CHORNET SARA; VELTY ALEXANDRA I LUCIENNE; CORMA CANOS AVELINO
摘要:A method for the synthesis of cyclic acetals comprises reacting at least one carbonyl-function compound selected from aldehydes, ketones, and/or linear acetals, on a polyol in a concentrated aqueous solution exceeding 20 wt % in a reactor containing an acidic catalyst. The carbonyl-function compound is selected so that the cyclic acetal obtained has a water solubility lower than 20000 mg/kg. During the catalytic reaction for the cyclic acetal synthesis, at least one portion of the organic phase containing the cyclic acetal is separated. The acidic catalysis is either homogeneous when using a water-soluble strong acid, or heterogeneous when using a solid acid such as a resin, a zeolite, or any appropriately acidified solid. The extractive reaction method can be used for obtaining high conversions and selectivity.

专利号:US-4347379-A
优先权日:1980-03-10
标 题:Synthesis of alpha-alkoxycarboxylic acids
发明人：LAI JOHN T
权利人:GOODRICH CO B F
摘要:Numerous alpha-carboxylic acids are prepared in a liquid medium by the reaction of an organic compound having at least one reactive hydroxyl or thiol group, with a monoketone, and a haloform, in the presence of a phase transfer catalyst and an alkali metal hydroxide. The term 'alpha-alkoxycarboxylic acids' includes alpha-phenoxycarboxylic acids, alpha-thioalkoxycarboxylic acids and alpha-thiophenoxycarboxylic acids. Specific substituents on the beta carbon atom of an alpha-alkoxycarboxylic (or '2-alkoxycarboxylic') acid reaction product formed in this novel synthesis, are introduced by appropriate choice of the ketone reactant; alkoxy and phenoxy substituents on the alpha carbon atom of a 2-alkoxycarboxylic acid are introduced by appropriate choice of the organic compound having a hydroxyl or thiol group. De-alkoxylation of the 2-alkoxycarboxylic acid yields alpha-beta monoolefinically unsaturated carboxylic acids which are necessarily alpha substituted, and may also be beta-substituted. It is now possible to produce, simply and conveniently, numerous substituted alpha-beta monolefinically unsaturated carboxylic acids with a variety of substituents on the alpha carbon atom, and, optionally on the beta carbon atom of these substituted carboxylic acids. Esters may also be conventionally derived from both the 2-alkoxycarboxylic acids, and the unsaturated carboxylic acids. During the phase transfer catalyzed synthesis of this invention, an intermediate acyl halide derivative is formed prior to the formation of the 2-alkoxycarboxylic acid reaction product. The formation of the acyl halide derivative allows the subsequent direct formation, in a modification of the same reaction, of 2-alkoxycarboxylic acid amides (or '2-alkoxycarbamides'), simply by adding a primary or secondary amine to the reaction mass. By dealkoxylation of the 2-alkoxycarbamides, specific, necessarily alpha-substituted and optionally beta-substituted acrylamides are synthesized which previously could be prepared, if at all, only with difficulty.

专利号:US-4855425-A
优先权日:1986-08-27
标题:Process for the selective synthesis of ethylene diamines
发明人：MARSELLA JOHN A
权利人:AIR PROD & CHEM
摘要:The present invention is a process for the selective synthesis of alkanediamines by reacting a secondary amine with an alkanediol. High conversions and high selectivity for the production of alkanediamines is achieved by carrying out the reaction in the presence of a compound or complex of ruthenium in the absence of an organic phosphine co-catalyst.

专利号:WO-2014059961-A1
优先权日:2012-10-15
标 题 :Method for the synchronous absorption of carbon dioxide from flue gas and synthesis of dialkyl carbonates and alkylene carbonates
发明人：BÃœTTNER HERMANN; Müller Jürgen; JONKER RAPHAEL; DOEDT SEBASTIAN; BOSSE TOBIAS; MAKRAN SEBASTIAN
权利人:BÃœTTNER HERMANN
摘要:The invention relates to a synchronous CCU method (carbon dioxide capture and utilisation) for the absorption of carbon dioxide from flue gas and other CO 2 -containing substance sources and simultaneous synthesis of dialkyl carbonates and alkylene carbonates. The general subject matter of the invention is, in terms of a 'carbon dioxide capture' on the one hand, the absorption of CO 2 from flue gas and other CO 2 -containing substance sources with ammonia and/or amines to form ammonium carbamates or ammonium hydrogen carbonates or ureas or urea intermediates and, in terms of a 'carbon dioxide utilisation' on the other hand, the reaction of ammonium carbamates or ammonium hydrogen carbonates or ureas or urea intermediates with aliphatic, alicyclic or unsaturated alcohols, and including unsaturated aromatic alcohols to give dialkyl carbonates or alkylene carbonates in such a form that the CO 2 n absorption agent is re-released and fed back into the repetitive process again. A repetitive process control is extremely energy and CO 2 n efficient.

专利号:US-4680393-A
优先权日:1986-05-08
标题 :Process for the selective synthesis of tertiary alkanolamines
发明人：MARSELLA JOHN A
权利人:AIR PRODUCTS AND CHAMICALS INC
摘要:The present invention is a process for the synthesis of tertiary alkanolamines by reacting a secondary amine with an alkanediol. High selectivity for the production of alkanolamines is achieved by carrying out the reaction in the presence of a compound or complex of ruthenium in chemical combination or in admixture with an organic phosphine ligand. The organic phosphine ligand is present in an amount such that the ratio of gram mole ligand/gram atom ruthenium is greater than 5.

专利号:US-2024082118-A1
优先权日:2021-05-19
标 题:Topical compositions and methods of preparing the same
发明人：ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.