CAS: 41464-49-7; 2,3,3',5'-Tetrachlorobiphenyl
该化合物是一种主要用于研究和工业应用的氯化联苯化合物,由于其稳定性和化学特性,主要用于研究和工业应用.作为多氯联苯(PCB)家族的成员,它充当环境和毒理学研究的参考标准,协助分析多氯联苯污染和降解途径.其明确的结构和纯度使它适合分析校准和方法验证.该化合物在环境矩阵中的持久性也使得可以研究生物累积和长期生态影响.由于国际多氯联苯管理准则对它的潜在毒性和监管限制,妥善处理至关重要.
- 英文名称2,3,3',5'-Tetrachlorobiphenyl
- 中文名称2,3,3'5'-四氯联苯
- IUPAC名称1,2-dichloro-3-(3,5-dichlorophenyl)benzene
- 其它别名2,3,3',5'-Tetrachlorobiphenyl; 2',3,3',5-Tetrachloro-1,1'-biphenyl; CB 58; PCB 58
- CAS编号41464-49-7
- MFCD编号:MFCD00152842
- FDA UNII编号:1K9F29DMH0
- 分子式:C12H6Cl4分子量:291.99
- 产品CID: 1428948
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
3,5-dichloroaniline hydr°Chloride 1,2-dichloro-benzene 2,3-dichloroaniline 1,3-Dichlorobenzene合成工艺路线路线简述
海关参考信息
- 2903911000-邻二氯苯
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合成参考文献
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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