CAS: 3638-64-0; Nitroethene

该化合物是一种反应性硝基苯,通常用作有机合成的中间体.甲苯的溶液具有稳定性和易处理性,适合Michael添加,循环添加和聚合等应用.硝基苯组会增强电益性,有助于核生殖攻击和促成多种功能化.标准化浓度(~1M)确保反应中对异异衡控制的连续反应性.托伦作为惰性溶剂,尽量减少不想要的副作用,同时保持溶性.这一产品在精细化学和制药研究中特别有用,因为受控的再活动性和纯度至关重要.建议在惰性条件下适当储存以保持稳定性.

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CAS号79-10-7 丙烯酸 | CAS号625-48-9 2-硝基乙醇 | CAS号39221-06-2 1-nitroethanol | CAS号625-47-8 2-Chloronitroethane | CAS号85-44-9 苯酐 | CAS号4528-34-1 2-nitroethyl nitrate | CAS号7570-26-5 1,2-dinitroethane | CAS号18942-89-7 1-acetoxy-2-nit... | CAS号50-00-0 甲醛 | CAS号75-52-5 硝基甲烷 | CAS号104543-10-4 2-(2-cyclohexyl... | CAS号7803-49-8 羟胺 | CAS号75-07-0 乙醛 | CAS号28364-56-9 N-hexan-3-ylide... | CAS号952-06-7 1,2-二苯基乙酮肟 | CAS号646-14-0 1-硝基己烷 | CAS号80242-09-7 decan-5-one oxime | CAS号636-09-9 对苯二甲酸二乙酯 | CAS号625-48-9 2-硝基乙醇 | CAS号34969-96-5 1-methyl-4-nitr...

合成工艺路线路线简述

  • 合成目标产物 Nitroethylene 主要起始原料 Acrylic Acid
  • (文献来源)合成步骤主要原料 Acrylic Acid
📜1-氯-2-硝基乙烷置于calcium Chloride体系中,化学反应生成 硝基乙烯
参考文献:Us2414594
标题:Us2414594

海关参考信息

专利信息


专利号:EP-0439404-B1
优先权日:1990-01-25
标题 :Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom
发明人:KHATRI HIRALAL N; DEHOFF BRADLEY S
权利人:SANOFI SA
摘要:An improved process for the synthesis of 2-(2 min -thienyl)ethylamine from suitably functionalized derivatives of 2-(2 min -thienyl)ethanol employing ammonia gas in the presence of a metal salt or liquid ammonia and alkyl ketone as a solvent. The 2-(2 min -thienyl)ethylamine produced by this process is advantageously converted to the carbamic acid salt, which is suitably reconverted to 2-(2 min -thienyl)ethylamine, a useful intermediate in the synthesis of ticlopidine.

专利号:US-5068360-A
优先权日:1990-01-25
标题 :Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom
发明人:DEHOFF BRADLEY S
权利人:SYNTEX INC
摘要:An improved process for the synthesis of 2-(2'-thienyl)ethylamine from suitably functionalized derivatives of 2-(2'-thienyl)ethanol employing ammonia gas in the presence of a metal salt or liquid ammonia and alkyl ketone as a solvent. The 2-(2'-thienyl)ethylamine produced by this process is advantageously converted to ticlopidine.

专利号:US-5191090-A
优先权日:1990-01-25
标题:Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom
发明人:DEHOFF BRADLEY S
权利人:SYNTEX INC
摘要:An improved process for the synthesis of 2-(2'-thienyl)ethylamine from suitably functionalized derivatives of 2-(2'-thienyl)ethanol employing ammonia gas in the presence of a metal salt or liquid ammonia and alkyl ketone as a solvent. The 2-(2'-thienyl)ethylamine produced by this process is advantageously converted to ticlopidine.

专利号:US-8450365-B2
优先权日:2009-05-12
标 题 :Efficient synthesis of galanthamine
发明人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

专利号:US-6770763-B2
优先权日:2002-06-11
标题 :Asymmetric synthesis of amino-pyrrolidinones
发明人:MAGNUS NICHOLAS A; CONFALONE PASQUALE N; SAVAGE SCOTT A; YATES MATTHEW; WALTERMIRE ROBERT E; MELONI DAVID J; CAMPAGNA SILVIO
权利人:BRISTOL MYERS SQUIBB CO
摘要:A novel process for the asymmetric synthesis of an amino-pyrrolidinone of the type shown below from appropriate pyrrolidinones is described.These compounds are useful as intermediates for MMP and TACE inhibitors.

专利号:WO-2016147205-A1
优先权日:2015-03-13
标题 :Novel substituted 3-spirophosphoryl pyrazole-2-oxindoles as anti-infectives and process for the synthesis thereof
发明人:SURYAVANSHI GURUNATH MALLAPPA; SHELKE ANIL MARUTI
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to novel substituted 3-spirophosphoryl, pyrazole-2-oxindoles of Formula (I) and its pharmaceutically acceptable salts, esters, ethers, isomers, stereoisomers, positional isomers and pplymorphs. The present invention further relates to one pot, one step process for the synthesis of spirophosphoiyl pyrazole oxindoles of Formula (I) with yield in the range of 70-85%.

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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Fringuelli, F.; Piermatti, O.; Pizzo, F.; Vaccaro, L., Science of Synthesis, (2010) 47, 631.
摘要:Chiba, S.; Narasaka, K., Science of Synthesis Knowledge Updates, (2011) 4, 455.
摘要:Duschmalé, J.; Arakawa, Y.; Wennemers, H., Science of Synthesis: Asymmetric Organocatalysis, (2012) 2, 772.
摘要:Nagasawa, K.; Sohtome, Y., Science of Synthesis: Asymmetric Organocatalysis, (2012) 2, 24.
摘要:Müller, T. J. J., Science of Synthesis: Multicomponent Reactions, (2013) 1, 15.
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