CAS: 33676-00-5; (7R,8R,9S)-9-(3,4-Dimethoxyphenyl)-4-Methoxy-7,8-Bis(Methoxymethyl)-6,7,8,9-Tetrahydrobenzo[g][1,3]Benzodioxole

该化合物是一种自然形成的化合物,被归类为氟氯素,特别是一种酚类化合物,主要来自植物物种Phyllanthus amarus,以其医学特性著称;Hypophlanthin展示了一系列生物活动,包括抗氧化剂,抗炎和肝保护效应,使其对药理学研究感兴趣;该化合物的特点是其复杂的分子结构,其中包括多种氢氧化物组,有助于其再活动以及与生物系统的互动;Hyphyllanthin在有机溶剂中可溶解,在水中溶解性有限,可影响其生物利用率和治疗应用;Hypyphylanthin研究强调了其在治疗肝病方面的潜力及其在传统医学中的作用,特别是在Pyllanthus物种流行的地区.与许多自然化合物一样,需要进一步研究,以充分阐明其行动和潜在治疗用途的机制.

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(6aR,9aR,10S)-5-Bromo-10-(3,4-dimethoxy-phenyl)-4-methoxy-6a,7,9a,10-tetrahydro-6H-furo[3',4':6,7]naphtho[1,2-d][1,3]dioxol-9-one methyl iodide r-1-(3,4-dimethoxyphenyl)-t-2,c-3-bishydroxymethyl-6-methoxy-7,8-methylenedioxy-1,2,3,4-tetrahydronaphthalene9-(3,4-Dimethoxy-phenyl)-4-methoxy-8-methoxymethyl-naphtho[1,2-d][1,3]dioxole-7-carbaldehyde (8R,9S)-9-(3,4-Dimethoxy-phenyl)-4-methoxy-8-methoxymethyl-8,9-dihydro-naphtho[1,2-d][1,3]dioxole-7-carbaldehyde

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    专利信息


    专利号:US-7829124-B2
    优先权日:2001-04-26
    标题:Use of Phyllanthus constituents for treating or preventing infections caused by hepatitis B-viruses
    发明人:OTT MICHAEL; MANNS MICHAEL P
    权利人:OTT MICHAEL; MANNS MICHAEL P
    摘要:The disclosure relates to a method of inhibiting synthesis of viral DNA in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting hepatitis B viral DNA synthesis in the mammal using the Phyllanthus component or substance. The disclosure also relates to a method of inhibiting viral gene expression in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting expression of at least one hepatitis B viral gene in the mammal using the Phyllanthus component or substance. These methods may form part of a method of preventing or treating hepatitis B infection.

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    ✅ COA系统入驻 | 共享模式

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    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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