CAS: 2753-45-9; Mebeverine Hydrochloride

该化合物是一种四硝基铵化合物,具有抗呼吸系统特性,主要用于治疗肠胃紊乱,如肠胃肠炎和功能性肠道扰动,其行动机制包括胃肠道的光滑肌肉直接放松,通过有选择地抑制磷化物酶和钙管的封闭而实现.这导致在不影响正常肠胃运动力的情况下,减少超机动性和抽筋.盐的盐形式提高了溶性性和生物利用率,确保了稳定的药用动能.水氯甲虫表现出最低限度的系统吸收,减少了不利影响的风险.其有针对性的行动和有利的安全特征使得它成为管理功能性胃肠状况的首选方案.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

    海关参考信息

    专利信息


    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

    专利号:CN-119431161-B
    优先权日:2024-11-28
    标题 :Synthesis method of mebeverine hydrochloride

    专利号:CN-119431161-A
    优先权日:2024-11-28
    标题:Synthesis method of mebeverine hydrochloride

    专利号:CN-119118851-A
    优先权日:2024-09-18
    标题:Synthesis method of mebeverine hydrochloride

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Mostafa GAE, El-Tohamy MF, Alrabiah H. Prospective of Agro-Waste Husks for Biogenic Synthesis of Polymeric-Based CeO2/NiO Nanocomposite Sensor for Determination of Mebeverine Hydrochloride. Molecules. 2023 Feb 23;28(5):2095. doi: 10.3390/molecules28052095.
    2: Milusheva M, Gledacheva V, Stefanova I, Pencheva M, Mihaylova R, Tumbarski Y, Nedialkov P, Cherneva E, Todorova M, Nikolova S. In Silico, In Vitro, and Ex Vivo Biological Activity of Some Novel Mebeverine Precursors. Biomedicines. 2023 Feb 17;11(2):605. doi: 10.3390/biomedicines11020605.
    3: Abdel-Raoof AM, Fouad MM, Rashed NS, Hosni NYZ, Elsonbaty A, Abdel-Fattah A. Potentiometric determination of mebeverine hydrochloride antispasmodic drug based on molecular docking with different ionophores host-guest inclusion as a theoretical study. RSC Adv. 2023 Jan 4;13(2):1085-1093. doi: 10.1039/d2ra06127a.

    合成参考文献


    摘要:German Offenlegungsschrift Patent Document., #2821584
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知