CAS: 261762-55-4; 2-(3-Chloro-2,6-Difluorophenyl)Acetonitrile
该化合物是一种有机化合物,其特点是芳香结构,包括一个以氯和氟原子替代的苯环,以及一个硝酸功能组;苯环上存在氯原子和两个氟原子,这助长了其独特的化学反应和物理特性,如电子增强和氢联结潜力;该化合物一般无色至浅黄色液体或固体,视其室温状况而定;在有机溶剂中溶解,在标准条件下可能表现出中度稳定性;硝酸盐组(-CN)具有额外的极性,影响其与其他化学物种的相互作用;由于其卤化性质,3-Croloto-2,6-二氟苯乙酸硝酸硝酸三硝酸三硝酸三烯还可能展示具体的生物活动,使其在各个领域,包括制药和农用化学物中具有兴趣;在处理该化合物时,应当采取安全防范措施,因为卤化化合物可能构成环境和健康风险.
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
2,6-difluoro-3-chlorobenzoic acid (3-chloro-2,6-difluoro-phenyl)-methanol sodium cyanide 3-chloro-2,6-difluorobenzyl bromide 3-(3-chloro-2,6-difluorophenyl)-7-((5-(2-(diethylamino)ethoxy)pyridin-2-yl)amino)-1-ethyl-1,6-naphthyridin-2(1H)-one ethyl 2-(3-chloro-2,6-difluorophenyl)acetate 7-chloro-3-(3-chloro-2,6-difluorophenyl)-1-ethyl-1,6-naphthyridin-2(1H)-one 8H5ClF2O2C8H5ClF2O2合成工艺路线路线简述
📜3-氯-2,6-二氟苯甲酸置于四溴化碳,Dimethyl Sulfide Borane,三苯基膦体系中,用 四氢呋喃,乙醇,二氯甲烷 用作溶剂,化学反应 16.0H,反应生成3-氯-2,6-二氟苯乙腈
参考文献: Multiple Kinase Pathway Inhibitors[fr] Inhibiteurs De Multiples Voies De Kinases
标题: Multiple Kinase Pathway Inhibitors[fr] Inhibiteurs De Multiples Voies De Kinases
摘要:对多种信号通路中的激酶具有抑制活性的激酶及其治疗用途.
海关参考信息
- 2902600000-乙苯
2903919090-氯苯
2926909090-其他腈基化合物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022267331-A1
优先权日:2019-06-05
标题 :Dopamine-b-hydroxylase inhibitors
发明人：KISS LASZLO; BELIAEV ALEXANDER; ROSSI TINO; PALMA NUNO; SOARES DA SILVA PATRÃ?CIO; PINTO RUI; CARDONA FRANCISCO
权利人:BIAL PORTELA & CA SA
摘要:This invention relates to: (a) compounds of formula I (with R1 to R5 and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-β-hydroxylase inhibitors; (b) pharmaceutical compositions comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.
专利号:US-11034695-B2
优先权日:2016-09-23
标 题:Dopamine-β-hydroxylase inhibitors
发明人：SOARES DA SILVA PATRÃ?CIO; ROSSI TINO; KISS LASZLO ERNO; BELIAEV ALEXANDER; LEAL PALMA PEDRO NUNO
权利人:BIAL—PORTELA & CA S A; BIAL—PORTELA & Cᵃ S A
摘要:This invention relates to: (a) compounds of Formula Ia (with R1, R4, R5, R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-β-hydroxylase inhibitors; (b) pharmaceutical compositions comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题: Dopamine-B-Hydroxylase Inhibitors Inhibiteurs De La Dopamine-B-Hydroxylase摘要:This Invention Relates To: (A) Compounds Of Formula Ia (With R1, R4, R5, R6, N And A As Defined Herein) And Pharmaceutically Acceptable Salts Or Solvates Thereof That Are Useful As Dopamine-β-Hydroxylase Inhibitors; (B) Pharmaceutical Compositions Comprising Such Compounds, Salts Or Solvates; (C) The Use Of Such Compounds, Salts Or Solvates In Therapy; (D) Therapeutic Methods Of Treatment Using Such Compounds, Salts Or Solvates; And (E) Processes And Intermediates Useful For The Synthesis Of Such Compounds.
📝 需求与反馈
尽可能描述清楚需求与问题信息
