CAS: 147769-93-5; (S)-3-Methyl-1-(2-(Piperidin-1-yl)Phenyl)Butan-1-Amine

相似化合物

1427475-24-8 219921-93-4 108157-52-4

上下游产品

(S)-1-(2-piperidino-phenyl)-3-methyl-1-butylamine -amineN-acetyl-N-(S)-3-methyl-1-(2-(1-piperidinyl)phenyl)-1-butyl-amine butyl>-N--amineN-(S)-3-methyl-1-2-(1-piperidinyl)phenylbutyl-N-(R')-1-phenethyl-amine butyl>-N--amineN-(S)-3-methyl-1-2-(1-pieridinyl)phenylbutyl-N-(S')-1-phenethyl-amine butyl>amino>-2-oxoethyl>-benzoate(S)-(+)-ethyl 2-ethoxy-4-2-3-methyl-1-2-(1-piperidinyl)phenylbutylamino-2-oxoethyl-benzoate -amineN-acetyl-N-(S)-3-methyl-1-(2-(1-piperidinyl)phenyl)-1-butyl-amine (S)-repaglinide 2-ethoxy-N-[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzamide

N-Acetyl-N-<(S)-3-Methyl-1-(2-(1-Piperidinyl)Phenyl)-1-Butyl>-Amine置于氨体系中,用 盐酸 用作溶剂,化学反应生成(S)-3-甲基-1-[2-(1-哌啶基)苯基]丁胺
参考文献:Phenylacetic Acid Benzylamides
标题:Phenylacetic Acid Benzylamides
摘要:本申请涉及苯乙酸苄胺和新的(S)(+)-2-乙氧基-4-[n-[1-2-哌啶基苯)-3-甲基-1-丁基]-氨基甲酰基]苯甲酸及其盐的用途,具有有价值的药理特性,即对中间代谢有影响,尤其是降低血糖的作用.

专利信息

专利号:WO-2007104357-A1
优先权日:2006-03-14
标 题 :Synthesis of amines with catalytic amounts of mild lewis acids
发明人：NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
权利人:UNIV JACOBS BREMEN GMBH; NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
摘要:The invention relates to methods for producing primary, secondary and tertiary amines and corresponding enantiopure or enantioenriched primary or secondary amine products, comprising the steps of reductively aminating a ketone, with a nitrogen auxiliary in the presence of a hydrogenating catalyst and a hydrogenating agent, wherein the reductive animation is performed under the influence of a mild Lewis acid, the mild Lewis acid being present at the onset of the reductive amination in at most 25 mol% of the ketone or the nitrogen auxiliary.

专利号:EP-2019097-A1
优先权日:2007-07-25
标 题 :Process for preparing (alphaS)-alpha-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine
发明人：MALLIKARJUNA REDDY KARURU; JAYATI MITRA; SIVAKUMARAN MEENAKSHISUNDERAM; RAMESH DANDALA
权利人:AUROBINDO PHARMA LTD
摘要:The present invention relates to a process for the preparation of (αS)-α-(2-methylpropyl)-2- (1-piperidinyl)benzenemethanamine of Formula I,n nwhich is a key intermediate for the synthesis of Repaglinide.

专利号:US-7041830-B2
优先权日:2003-03-31
标 题 :Process for preparing (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine
发明人：KALKOTE UTTAM RAMRAO; GURJAR MUKUND KESHAO; JOSHI SHREERANG VIDYADHAR; KADAM SURESH MAHADEV; MONDKAR HARISH KASHINATH
权利人:COUNCIL SCIENT IND RES
摘要:The Present invention relates to a process for the preparation of (RS) 3-methyl-1-(2-piperidinyl phenyl) butyl amine of formula 1. n n n n n n n n n n (RS) 3-Methyl-1-(2-piperidinyl phenyl butyl amine having formula 1 is an important key intermediate for the synthesis of repaglinide of formula 2 an oral hypoglycemic agent.

专利号:CN-102633750-A
优先权日:2012-03-26
标 题 :One-pot synthesis of repaglinide, a drug for treating diabetes

专利号:WO-2007104359-A1
优先权日:2006-03-14
标 题:Synthesis of amines with ytterbium lewis acids
发明人：NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN
权利人:UNIV JACOBS BREMEN GMBH; NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN
摘要:The invention relates to methods for producing primary, secondary, and tertiary amines and the corresponding enantiopure or enantioenriched primary or secondary amine products from secondary or tertiary amine diastereomers.

专利号:EP-0965591-A1
优先权日:1991-06-21
标 题 :(s)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine, its salts, synthesis and use in the long term therapy of diabetes mellitus