CAS: 13192-04-6; Dimethyl 2-Oxoglutarate

上下游产品

Alpha-酮戊二酸 α-Ketoglutaric Acid 328-50-7

Alpha-酮戊二酸 以 甲醇,苯 用作溶剂,化学反应 0.5H,以85%的收率获得alpha-酮戊二酸二甲酯
参考文献:Mashimoto,Norio; Aoyama,Toyohiko; Shioiri,Takayuki,Chemical And Pharmaceutical Bulletin,1981,Vol. 29,# 5,P. 1475-1478
标题:Mashimoto,Norio; Aoyama,Toyohiko; Shioiri,Takayuki,Chemical And Pharmaceutical Bulletin,1981,Vol. 29,# 5,P. 1475-1478

专利信息

专利号:US-10799441-B2
优先权日:2011-06-06
标题:Skin treatments containing pyrroloquinoline quinone (PQQ) esters and methods of preparation and use thereof
发明人：LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C
权利人:LEWIS II JOSEPH ABERNATHY; DINARDO JOSEPH C; PCR TECH HOLDINGS LC
摘要:The present invention relates to cosmetic or dermatological compositions containing PQQ or its esters, methods of treating or promoting skin changes by topical application of these compositions, and methods of synthesis of PQQ esters. The PQQ ester-containing compositions of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the PQQ esters of the present invention have an antioxidant effect that is useful in treating a skin change.

专利号:US-11999693-B2
优先权日:2015-09-24
标 题:Synthetic sphingolipid-like molecules, drugs, methods of their synthesis and methods of treatment
发明人：EDINGER AIMEE L; HANESSIAN STEPHEN
权利人:UNIV CALIFORNIA; THE UNIV DE MONTREAL
摘要:Small molecules comprised of azacyclic constrained sphingolipid-like compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.

专利号:US-10807979-B2
优先权日:2017-05-11
标题:4,5-disubstituted-1H-pyrrolo(2,3-f)quinolin-2,7,9-tricarboxylate compound and use thereof
发明人：WANG JINGLIN; QIN SONG; MU ZHENQIANG; LI YANG
权利人:SHANDONG CAMASY BIOTECHNOLOGY CO LTD; SHANGDONG CAMASY BIOTECHNOLOGY CO LTD
摘要:A 4,5-disubstituted-1H-pyrrolo(2,3-f)quinolin-2,7,9-tricarboxylate compound, or an analog, or derivative thereof, having a structure of Formula I: n nR 1 and R 4 are each independently an atom or group selected from hydrogen, a linear or branched C1-8 alkyl group, a deuterated linear or branched C1-8 alkyl group, an aralkyl group, or a substituted aryl group; R 2 is independently an atom or group selected from halogens, a linear or branched C1-8 alkoxy group, or a deuterated linear or branched C1-8 alkoxy group; and R 3 is independently an atom or group selected from a linear or branched C1-8 alkoxy group, or a deuterated linear or branched C1-8 alkoxy group. The compound is useful as a reaction intermediate for the synthesis of PQQ. A process in which CAN is used as an oxidant in the synthesis of PQQ in existing patents and literatures is replaced. This makes the process cheaper and more efficient.

专利号:MX-PA03008645-A
优先权日:2002-09-24
标 题:NEW PROCESS FOR THE INDUSTRIAL SYNTHESIS OF THE METHYLIC DIESTER OF ACID 5-AMINO-3-CARBOXIMETIL-4-CIANO-2-THIOFENCARBOXILICO, AND APPLICATION TO THE SYNTHESIS OF BIVALENT SALES OF RANELIC ACID AND ITS HYDRATS.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:US-2007072894-A1
优先权日:2005-03-24
标题:Synthesis of pyrroloquinoline quinone (PQQ)
发明人：KEMPF J V; GOPAL DAMODARA; STALZER WALTER
权利人:KEMPF J V; GOPAL DAMODARA; STALZER WALTER
摘要:The invention relates to a novel nine step process for synthesizing PQQ (methoxatin). This process is efficient and reliably provides PQQ in excellent purity and high yield.