CAS: 114798-26-4; (1-((2'-(1H-Tetrazol-5-yl)-[1,1'-Biphenyl]-4-yl)Methyl)-2-Butyl-4-Chloro-1H-Imidazol-5-yl)Methanol

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CAS号124751-00-4 [2-丁基-4-氯-1-[(2... | CAS号114772-55-3 4'-[(2-丁基-4-氯-5... | CAS号114798-36-6 氯沙坦甲醛 | CAS号124750-99-8 氯沙坦钾 | CAS号133909-99-6 N-Trityl Losart... | CAS号67-56-1 甲醇 | CAS号852357-69-8 (2-butyl-5-chlo... | CAS号18039-42-4 5-苯基四氮唑 | CAS号41882-10-4 N-(4-methoxyben... | CAS号1070175-00-6 3-(methanesulfo... | CAS号2387-23-7 N,N’-二环己基脲 | CAS号1070174-97-8 4-(3-thioxo-3H-... | CAS号124751-00-4 [2-丁基-4-氯-1-[(2... | CAS号138584-34-6 氯沙坦N1-葡萄糖醛酸 | CAS号138584-35-7 氯沙坦N2-葡萄糖醛酸 | CAS号124750-99-8 氯沙坦钾 | CAS号124750-92-1 氯沙坦

Cozaar置于10体系中,用 水 用作溶剂,化学反应 336.0H,以to Obtain A Concentration Of 2.5 Mg/ml的收率获得洛沙坦
参考文献:Novel Compositions And Uses Of Anti-Hypertension Agents For Cancer Therapy
标题:Novel Compositions And Uses Of Anti-Hypertension Agents For Cancer Therapy
摘要:本发明揭示了用于改善治疗(例如癌症治疗)的递送和/或疗效的方法和组合物.在一种实施例中,揭示了通过向受试者施用降压药物(作为单一药物或与微环境调节剂和/或治疗(例如,治疗剂或治疗疗法,包括免疫疗法(例如,抗体,疫苗,基于细胞的疗法),纳米治疗,放射线治疗,光动力疗法,低分子量化疗药物,分子靶向治疗和/或氧自由基)组合使用)来治疗或预防癌症(例如,实质性肿瘤如纤维化瘤)的方法和组合物.

专利信息

专利号:US-10889599-B2
优先权日:2018-02-27
标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds
发明人：CHO SEUNG HWAN; LEE YEOSAN
权利人:POSTECH ACAD IND FOUND
摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-10973847-B2
优先权日:2017-06-30
标题 :Core-to-surface polymerization for the synthesis of star polymers and uses thereof
发明人：JOHNSON JEREMIAH A; GOLDER MATTHEW R
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Disclosed are methods, compositions, reagents, systems, and kits to prepare star polymers, as well as compositions and uses thereof. Various embodiments show that synthesis of these polymers contain low metal concentration to provide polymers for diverse biomedical applications including in vivo applications.

专利号:US-2008214637-A1
优先权日:2004-11-11
标题 :Process for the Synthesis of Tetrazoles
发明人：ANTONCIC LJUBOMIR; LUDESCHER JOHANNES
权利人:LEK PHARMACEUTICALS
摘要:A process for the synthesis of tetrazol derivative has been developed which starts from a tetrazole derivative where acidic hydrogen atom has been replaced by a protecting group and the deprotection is performed with a catalytic amount of organic acid and can proceed in an aqueous solvent.

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-6271375-B1
优先权日:1997-06-30
标 题 :Ortho-metalation process for the synthesis of 2-substituted-1-(tetrazol-5-yl)benzenes
发明人：VILLA MARCO; ALLEGRINI PIETRO; ARRIGHI KATIUSCIA; PAIOCCHI MAURIZIO
权利人:ZAMBON SPA
摘要:A process of direct metalation of phenyltetrazoles useful for preparing compounds of formula (II) intermediates for the synthesis of angiotensin II antagonists is described.