专利号:US-2011124634-A1 优先权日:2008-05-13 标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases 发明人:SUN CONNIE L; LI XIAOYUAN 权利人:PONIARD PHARMACEUTICALS INC 摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.
专利号:US-11034677-B2 优先权日:2015-01-20 标 题:Coumarin-based compounds and related methods 发明人:SANCHEZ ANTHONY DE JESUS 权利人:BIOSEARCH TECH INC 摘要:The present invention generally relates to coumarin-based compounds that can be used for the labeling of biological molecules, as well as related synthetic and testing methods. The coumarin-based compounds typically survive conditions necessary for automated synthesis of nucleic acids without undergoing any substantial degree of degradation or alteration.
专利号:DE-1695956-A1 优先权日:1965-09-29 标题 :Process for the in vitro synthesis of biologically active intact nucleic acids and the production of replicases which are suitable for this
专利号:US-2005113397-A1 优先权日:2002-01-31 标题:Imidazo[1,2-a]pyridine derivative 发明人:TAKEMURA MAKOTO; TAKAHASHI HISASHI; KAWAKAMI KATSUHIRO; TAKESHITA HIROSHI; KIMURA YOUICHI; WATANABE JUN; SUGIMOTO YUICHI; KITAMURA AKIHIRO; NAKAJIMA RYOHEI; KANAI KAZUO; FUJISAWA TETSUNORI 摘要:A compound reprsented by the following formula (I), its salts or nsolvates thereof capable of specifically or selectively expressig an antifungal activity in a broad spectrum based on the novel mechanism thereof of 1,6-β-glucan synthesis inhibition, and an antifungal agent containing any of them.
专利号:CN-105348056-B 优先权日:2015-12-11 标题:A kind of method of two-phase synthesis 2,5 hexanedione
专利号:RU-2113437-C1 优先权日:1991-10-24 标 题:Substituted pyrimidines or their pharmaceutically acceptable salts, or n-oxides, methods of their synthesis and pharmaceutical composition based on thereof